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Tdark
CCDC73
Coiled-coil domain-containing protein 73

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000335185
  • ENSP00000335325
  • ENSG00000186714

Symbol
  • NY-SAR-79
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.82
virus perturbation
0.64
small molecule perturbation
0.58
cell line
0.56
gene perturbation
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.13   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.13   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
CTAG1A
Tbio
Novelty:  0.00345306
Score:  0.8
Data Source:  STRINGDB
KANK3
Tdark
Novelty:  0.35969246
Score:  0.742
Data Source:  STRINGDB
QSER1
Tdark
Novelty:  0.62017582
Score:  0.711
Data Source:  STRINGDB
TCP11L1
Tdark
Novelty:  1.5011461
Score:  0.704
Data Source:  STRINGDB
PRSS55
Tbio
Family:  Enzyme
Novelty:  0.20503445
Score:  0.703
Data Source:  STRINGDB
C6orf201
Tdark
Novelty:  51
Score:  0.669
Data Source:  STRINGDB
PRRG4
Tdark
Novelty:  0.19371546
Score:  0.669
Data Source:  STRINGDB
DEPDC7
Tdark
Novelty:  0.28944316
Score:  0.636
Data Source:  STRINGDB
CCDC42
Tdark
Novelty:  0.55978513
Score:  0.632
Data Source:  STRINGDB
TEX37
Tdark
Novelty:  0.24100699
Score:  0.608
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
1
1
1
69.2
platelet count
1
1
1
56.2
sex hormone-binding globulin measurement
1
1
1
35
1
1
0
1
21.5
1
1
0
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
1
69.2
platelet count
1
56.2
sex hormone-binding globulin measurement
1
35
0
1
21.5
0
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 73
VGNC:3169
466481
Macaque
coiled-coil domain containing 73
694826
Mouse
MGI:3606488
211936
Rat
RGD:1563448
499848
Dog
coiled-coil domain containing 73
VGNC:38854
483438
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 73
Macaque
coiled-coil domain containing 73
Mouse
Rat
Dog
coiled-coil domain containing 73
Publication Statistics
PubMed Score 1.13
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title