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Tdark
CCDC51
Coiled-coil domain-containing protein 51

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000395694
  • ENSP00000379047
  • ENSG00000164051
  • ENST00000412398
  • ENSP00000401194
  • ENST00000442740
  • ENSP00000392898
  • ENST00000447018
  • ENSP00000412300
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
histone modification site profile
0.74
tissue sample
0.73
kinase perturbation
0.6
transcription factor binding site profile
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.83   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.83   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (57)
IL1R2
Tbio
Novelty:  0.00820359
p_int:  0.999998727
p_ni:  0.000001273
Data Source:  BioPlex
PCDH20
Tbio
Novelty:  0.07862843
p_int:  0.999996189
p_ni:  0.000003811
Data Source:  BioPlex
CEACAM21
Tdark
Novelty:  0.46116153
p_int:  0.999983335
p_ni:  0.000016664
p_wrong:  1e-9
Data Source:  BioPlex
YOD1
Tbio
Family:  Enzyme
Novelty:  0.05709057
p_int:  0.999978058
p_ni:  0.00002194
p_wrong:  2e-9
Score:  0.217
Data Source:  BioPlex,STRINGDB
PTPRN
Tbio
Family:  Enzyme
Novelty:  0.00076479
p_int:  0.999967763
p_ni:  0.000032207
p_wrong:  3e-8
Data Source:  BioPlex
WDFY2
Tbio
Novelty:  0.01835759
p_int:  0.999670445
p_ni:  0.000329555
Data Source:  BioPlex
PLBD1
Tdark
Family:  Enzyme
Novelty:  0.27639575
p_int:  0.9996655
p_ni:  0.0003345
Score:  0.191
Data Source:  BioPlex,STRINGDB
EVA1B
Tdark
Novelty:  2.1380272
p_int:  0.998958158
p_ni:  0.001041839
p_wrong:  3e-9
Data Source:  BioPlex
SERPINB2
Tbio
Novelty:  0.00204345
p_int:  0.998588478
p_ni:  0.001411521
Data Source:  BioPlex
IL7R
Tbio
Novelty:  0.00107223
p_int:  0.998396621
p_ni:  0.001016875
p_wrong:  0.000586504
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
2
2
82
mathematical ability
3
2
4
81.6
BMI-adjusted waist circumference
1
2
2
81
BMI-adjusted waist-hip ratio
2
2
2
79.6
macrophage inflammatory protein 1b measurement
1
1
1
74.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
82
mathematical ability
4
81.6
BMI-adjusted waist circumference
2
81
BMI-adjusted waist-hip ratio
2
79.6
macrophage inflammatory protein 1b measurement
1
74.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 51
VGNC:1760
742241
Mouse
MGI:1913908
66658
Rat
RGD:1311466
316008
Dog
coiled-coil domain containing 51
VGNC:38841
609083
Horse
coiled-coil domain containing 51
VGNC:16166
100063856
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 51
Mouse
Rat
Dog
coiled-coil domain containing 51
Horse
coiled-coil domain containing 51
Publication Statistics
PubMed Score 1.83
PubMed score by year
PubTator Score 0.17
PubTator score by year
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Related Publications
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PMID
Year
Title