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Tdark
CCDC146
Coiled-coil domain-containing protein 146

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000285871
  • ENSP00000285871
  • ENSG00000135205

Symbol
  • KIAA1505
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.78
tissue sample
0.68
cellular component
0.63
cell line
0.62
cell type or tissue
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.44   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.44   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
GMNN
Tbio
Novelty:  0.00436572
p_int:  0.999910449
p_ni:  0.000089551
Score:  0.241
Data Source:  BioPlex,STRINGDB
RAB3IP
Tbio
Novelty:  0.04046982
p_int:  0.999461868
p_ni:  0.000477882
p_wrong:  0.00006025
Score:  0.513
Data Source:  BioPlex,STRINGDB
C4orf47
Tdark
Novelty:  4.70710026
Score:  0.789
Data Source:  STRINGDB
CFAP20
Tbio
Novelty:  0.01299681
Score:  0.779
Data Source:  STRINGDB
CCDC40
Tbio
Novelty:  0.06726469
Score:  0.753
Data Source:  STRINGDB
CCDC96
Tdark
Novelty:  1.08306736
Score:  0.751
Data Source:  STRINGDB
WDR90
Tdark
Novelty:  0.39919716
Score:  0.749
Data Source:  STRINGDB
C7orf31
Tdark
Novelty:  1.72375691
Score:  0.71
Data Source:  STRINGDB
CCDC38
Tdark
Novelty:  0.55483644
Score:  0.692
Data Source:  STRINGDB
CCDC113
Tdark
Novelty:  1.10748096
Score:  0.636
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
0
1
60.8
comparative body size at age 10, self-reported
1
1
1
60.2
1
1
0
1.1
58.4
body mass index
2
2
2
58.3
2
1
0
1
48.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1
60.8
comparative body size at age 10, self-reported
1
60.2
0
1.1
58.4
body mass index
2
58.3
0
1
48.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 146
VGNC:4301
463493
Macaque
coiled-coil domain containing 146
694907
Mouse
MGI:1922422
75172
Rat
Dog
coiled-coil domain containing 146
VGNC:38798
610021
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 146
Macaque
coiled-coil domain containing 146
Mouse
Rat
Dog
coiled-coil domain containing 146
Publication Statistics
PubMed Score 1.44
PubMed score by year
PubTator Score 1.10
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title