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Tdark
CCDC138
Coiled-coil domain-containing protein 138

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.34   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.34   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
MED4
Tbio
Family:  Enzyme
Novelty:  0.01200585
p_int:  0.999997921
p_ni:  0.000002079
Score:  0.296
Data Source:  BioPlex,STRINGDB
DCTN2
Tbio
Novelty:  0.01045432
p_int:  0.999953993
p_ni:  0.000010544
p_wrong:  0.000035463
Score:  0.211
Data Source:  BioPlex,STRINGDB
TXLNA
Tbio
Novelty:  0.02549959
p_int:  0.999940111
p_ni:  0.000059888
p_wrong:  1e-9
Data Source:  BioPlex
PBXIP1
Tbio
Novelty:  0.15404864
p_int:  0.999440296
p_ni:  0.000547966
p_wrong:  0.000011738
Data Source:  BioPlex
NUP62
Tbio
Novelty:  0.01432724
p_int:  0.998642828
p_ni:  0.001355171
p_wrong:  0.000002001
Data Source:  BioPlex
PCM1
Tbio
Novelty:  0.02901589
p_int:  0.998573127
p_ni:  0.001413473
p_wrong:  0.0000134
Data Source:  BioPlex
STX12
Tbio
Novelty:  0.03836262
p_int:  0.993856964
p_ni:  0.000002628
p_wrong:  0.006140408
Score:  0.181
Data Source:  BioPlex,STRINGDB
USP28
Tchem
Family:  Enzyme
Novelty:  0.02432294
p_int:  0.984761255
p_ni:  0.014021315
p_wrong:  0.00121743
Data Source:  BioPlex
FAM9B
Tdark
Novelty:  0.39508009
p_int:  0.934202609
p_ni:  0.064079378
p_wrong:  0.001718014
Data Source:  BioPlex
PAK5
Tchem
Family:  Kinase
Novelty:  0.02138632
p_int:  0.761750618
p_ni:  0.000014092
p_wrong:  0.23823529
Score:  0.187
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair morphology measurement
1
1
0
3.3
87.3
balding measurement
1
1
1
66
synophrys measurement
1
1
1
64.4
lobe size
1
1
1
55.2
helix rolling
1
1
1
55.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair morphology measurement
0
3.3
87.3
balding measurement
1
66
synophrys measurement
1
64.4
lobe size
1
55.2
helix rolling
1
55.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 138
VGNC:182
459479
Macaque
coiled-coil domain containing 138
694943
Mouse
MGI:1923388
76138
Rat
RGD:1566050
499442
Dog
coiled-coil domain containing 138
VGNC:38794
610991
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 138
Macaque
coiled-coil domain containing 138
Mouse
Rat
Dog
coiled-coil domain containing 138
Publication Statistics
PubMed Score 0.34
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title