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Tdark
CCDC127
Coiled-coil domain-containing protein 127

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296824
  • ENSP00000296824
  • ENSG00000164366
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.99
cellular component
0.68
transcription factor perturbation
0.68
tissue sample
0.61
cell line
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.49   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.49   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
PBXIP1
Tbio
Novelty:  0.15404864
p_int:  0.999999956
p_ni:  7e-9
p_wrong:  3.7e-8
Data Source:  BioPlex
CHCHD4
Tbio
Novelty:  0.01204944
p_int:  0.997252421
p_ni:  1.72e-7
p_wrong:  0.002747407
Data Source:  BioPlex
CEBPZOS
Tdark
Novelty:  11.11111111
Score:  0.701
Data Source:  STRINGDB
COA7
Tbio
Family:  Enzyme
Novelty:  0.08512811
Score:  0.639
Data Source:  STRINGDB
LRRC14B
Tdark
Novelty:  7.10619267
Score:  0.603
Data Source:  STRINGDB
EOGT
Tbio
Family:  Enzyme
Novelty:  0.08290891
Score:  0.546
Data Source:  STRINGDB
LMOD3
Tbio
Novelty:  0.06244763
Score:  0.531
Data Source:  STRINGDB
CCSMST1
Tdark
Novelty:  0.60610244
Score:  0.523
Data Source:  STRINGDB
FRMD4B
Tbio
Novelty:  0.20691438
Score:  0.516
Data Source:  STRINGDB
TMF1
Tbio
Novelty:  0.02543575
Score:  0.497
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
2
3
3
45.5
body weight
1
1
1
22.8
BMI-adjusted waist circumference
1
1
1
18.4
sex hormone-binding globulin measurement
1
1
1
1.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
3
45.5
body weight
1
22.8
BMI-adjusted waist circumference
1
18.4
sex hormone-binding globulin measurement
1
1.1
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 127
VGNC:3932
741389
Mouse
MGI:1914683
67433
Rat
RGD:735106
308060
Dog
coiled-coil domain containing 127
VGNC:38789
100684488
Horse
coiled-coil domain containing 127
VGNC:16119
100057272
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 127
Mouse
Rat
Dog
coiled-coil domain containing 127
Horse
coiled-coil domain containing 127
Publication Statistics
PubMed Score 0.49
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title