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Tdark
CCDC126
Coiled-coil domain-containing protein 126

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307471
  • ENSP00000304355
  • ENSG00000169193
  • ENST00000409765
  • ENSP00000386675
  • ENST00000410069
  • ENSP00000386355
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.77
gene perturbation
0.74
transcription factor binding site profile
0.74
tissue sample
0.61
histone modification site profile
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
GPM6A
Tbio
Novelty:  0.04123799
p_int:  0.999999737
p_ni:  2.63e-7
p_wrong:  1e-9
Score:  0.217
Data Source:  BioPlex,STRINGDB
MFF
Tbio
Novelty:  0.00411615
p_int:  0.999999078
p_ni:  9.07e-7
p_wrong:  1.5e-8
Score:  0.54
Data Source:  BioPlex,STRINGDB
PCMTD1
Tbio
Family:  Enzyme
Novelty:  0.14517534
Score:  0.578
Data Source:  STRINGDB
GCNT2
Tbio
Family:  Enzyme
Novelty:  0.03945461
Score:  0.551
Data Source:  STRINGDB
B3GNT7
Tbio
Family:  Enzyme
Novelty:  0.18258991
Score:  0.55
Data Source:  STRINGDB
B4GALNT1
Tbio
Family:  Enzyme
Novelty:  0.01060447
Score:  0.536
Data Source:  STRINGDB
TCEAL7
Tbio
Novelty:  0.14952824
Score:  0.528
Data Source:  STRINGDB
ZNF713
Tdark
Family:  TF
Novelty:  0.53817745
Score:  0.51
Data Source:  STRINGDB
ENHO
Tbio
Novelty:  0.01106852
Score:  0.492
Data Source:  STRINGDB
MAN1A2
Tbio
Family:  Enzyme
Novelty:  0.15637608
Score:  0.483
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
1
2
2
47.5
alkaline phosphatase measurement
1
1
0
5.7
24.5
myeloid white cell count
1
1
1
11.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
2
47.5
alkaline phosphatase measurement
0
5.7
24.5
myeloid white cell count
1
11.3
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 126
VGNC:4298
746731
Macaque
coiled-coil domain containing 126
710357
Mouse
MGI:1889376
57895
Rat
RGD:1561171
500117
Dog
coiled-coil domain containing 126
VGNC:38788
100688561
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 126
Macaque
coiled-coil domain containing 126
Mouse
Rat
Dog
coiled-coil domain containing 126
Publication Statistics
PubMed Score 0.47
PubMed score by year
PubTator Score 0.70
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title