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Tdark
CCDC102B
Coiled-coil domain-containing protein 102B

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.82   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 112   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.82   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 112   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (70)
TARSL2
Tbio
Family:  Enzyme
Novelty:  0.02406282
p_int:  0.999998986
p_ni:  0.000001014
Data Source:  BioPlex
GULP1
Tbio
Novelty:  0.01367525
p_int:  0.999994743
p_ni:  0.000005248
p_wrong:  9e-9
Score:  0.181
Data Source:  BioPlex,STRINGDB
USF2
Tbio
Family:  TF
Novelty:  0.00516415
p_int:  0.999993798
p_ni:  0.000005925
p_wrong:  2.77e-7
Score:  0.181
Data Source:  BioPlex,STRINGDB
ZNF622
Tbio
Novelty:  0.26258288
p_int:  0.999924858
p_ni:  0.000075107
p_wrong:  3.4e-8
Score:  0.181
Data Source:  BioPlex,STRINGDB
SNX1
Tbio
Novelty:  0.01267973
p_int:  0.999761369
p_ni:  0.000238631
Data Source:  BioPlex
TJP1
Tbio
Novelty:  0.00040365
p_int:  0.999721211
p_ni:  0.000278788
p_wrong:  1e-9
Data Source:  BioPlex
HDLBP
Tbio
Novelty:  0.00979636
p_int:  0.999538889
p_ni:  0.000461111
Data Source:  BioPlex
FGD6
Tbio
Novelty:  0.07213159
p_int:  0.99951383
p_ni:  0.00001602
p_wrong:  0.00047015
Score:  0.189
Data Source:  BioPlex,STRINGDB
TAB2
Tbio
Family:  Enzyme
Novelty:  0.00635786
p_int:  0.998643994
p_ni:  0.001356003
p_wrong:  4e-9
Data Source:  BioPlex
SAMD1
Tdark
Novelty:  0.21956379
p_int:  0.998364123
p_ni:  0.001635877
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
myopic maculopathy severity measurement
1
1
0
1.4
10.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
myopic maculopathy severity measurement
0
1.4
10.9
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
coiled-coil domain containing 102B
710808
Dog
coiled-coil domain containing 102B
VGNC:38776
483942
Horse
coiled-coil domain containing 102B
VGNC:16106
100059944
Opossum
coiled-coil domain containing 102B
100020325
Species
Name
OMA
EggNOG
Inparanoid
Macaque
coiled-coil domain containing 102B
Dog
coiled-coil domain containing 102B
Horse
coiled-coil domain containing 102B
Opossum
coiled-coil domain containing 102B
Publication Statistics
PubMed Score 3.82
PubMed score by year
PubTator Score 1.70
PubTator score by year
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Related Publications
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PMID
Year
Title