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Tdark
CBWD2
COBW domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000259199
  • ENSP00000259199
  • ENSG00000136682
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.75
molecular function
0.73
tissue sample
0.54
histone modification site profile
0.49
cell line
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 41   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
CBWD1
Tbio
Novelty:  0.04321511
p_int:  0.999999868
p_ni:  1.32e-7
Score:  0.586
Data Source:  BioPlex,STRINGDB
METAP1
Tchem
Family:  Enzyme
Novelty:  0.01816253
p_int:  0.999934831
p_ni:  0.000065169
Score:  0.866
Data Source:  BioPlex,STRINGDB
TUBB1
Tclin
Novelty:  0.02806117
p_int:  0.999606809
p_ni:  0.000393191
Data Source:  BioPlex
CACHD1
Tdark
Novelty:  0.56021668
p_int:  0.859544687
p_ni:  0.140455313
Score:  0.243
Data Source:  BioPlex,STRINGDB
TCERG1
Tbio
Novelty:  0.01721248
p_int:  0.822639632
p_ni:  0.177360368
Score:  0.855
Data Source:  BioPlex,STRINGDB
HSPA12A
Tbio
Novelty:  0.11999085
p_int:  0.784523955
p_ni:  0.215476028
p_wrong:  1.7e-8
Score:  0.694
Data Source:  BioPlex,STRINGDB
SFTA2
Tdark
Novelty:  0.24469271
p_int:  0.751771091
p_ni:  0.248228909
Score:  0.692
Data Source:  BioPlex,STRINGDB
CBWD6
Tdark
Novelty:  8.14063875
Score:  0.873
Data Source:  STRINGDB
EGLN1
Tclin
Novelty:  0.00236525
Score:  0.807
Data Source:  STRINGDB
WASH2P
Tdark
Novelty:  2.49106532
Score:  0.726
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep duration
3
1
3
24.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep duration
3
24.3
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
COBW domain-containing protein 1
739761
Species
Name
OMA
EggNOG
Inparanoid
Chimp
COBW domain-containing protein 1
Publication Statistics
PubMed Score 0.12
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title