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Tbio
CBLN4
Cerebellin-4

Protein Summary
Description
May be involved in synaptic functions in the CNS. May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity). This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000064571
  • ENSP00000064571
  • ENSG00000054803

Symbol
  • CBLNL1
  • CBLNL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.97
PubMedID
0.58
cell type or tissue
0.5
microRNA
0.48
cell line
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.89   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 102   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.89   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 102   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (94)
TOPBP1
Tbio
Family:  Enzyme
Novelty:  0.00735579
p_int:  1
Score:  0.206
Data Source:  BioPlex,STRINGDB
Q9HDB5
Tbio
Novelty:  0.00999084
p_int:  0.999972805
p_ni:  0.000027185
p_wrong:  9e-9
Score:  0.593
Data Source:  BioPlex,STRINGDB
GTF2F2
Tbio
Novelty:  0.02446629
p_int:  0.999936583
p_ni:  0.000057107
p_wrong:  0.00000631
Score:  0.206
Data Source:  BioPlex,STRINGDB
NKIRAS1
Tbio
Family:  Enzyme
Novelty:  0.11289799
p_int:  0.999817627
p_ni:  0.000182371
p_wrong:  2e-9
Score:  0.206
Data Source:  BioPlex,STRINGDB
NDUFAF2
Tclin
Novelty:  0.04815608
p_int:  0.999708883
p_ni:  9.92e-7
p_wrong:  0.000290125
Score:  0.39
Data Source:  BioPlex,STRINGDB
DHFR2
Tbio
Family:  Enzyme
Novelty:  0.02374466
p_int:  0.999513881
p_ni:  0.000468269
p_wrong:  0.000017851
Data Source:  BioPlex
C1QL1
Tdark
Novelty:  0.11689088
p_int:  0.996449115
p_ni:  0.003092565
p_wrong:  0.000458321
Score:  0.203
Data Source:  BioPlex,STRINGDB
ADAM11
Tbio
Family:  Enzyme
Novelty:  0.122537
p_int:  0.983124519
p_ni:  0.016802381
p_wrong:  0.000073099
Score:  0.437
Data Source:  BioPlex,STRINGDB
LRIF1
Tdark
Novelty:  0.26861958
p_int:  0.961571242
p_ni:  0.038413717
p_wrong:  0.00001504
Data Source:  BioPlex
GNB2
Tbio
Novelty:  0.08682553
p_int:  0.924880315
p_ni:  0.075105239
p_wrong:  0.000014446
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cerebellin 4 precursor
VGNC:6071
745662
Macaque
cerebellin 4 precursor
698567
Mouse
MGI:2154433
228942
Rat
RGD:1589642
499947
Dog
cerebellin 4 precursor
VGNC:54283
611731
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cerebellin 4 precursor
Macaque
cerebellin 4 precursor
Mouse
Rat
Dog
cerebellin 4 precursor
Publication Statistics
PubMed Score 8.89
PubMed score by year
PubTator Score 3.29
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title