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Tdark
CATSPERE
Cation channel sperm-associated protein subunit epsilon

Protein Summary
Description
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366531
  • ENSP00000355489
  • ENSG00000179397
  • ENST00000366533
  • ENSP00000355491
  • ENST00000366534
  • ENSP00000355492

Symbol
  • C1orf101
  • C1orf101
  • C10orf101
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.1   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.1   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
CATSPERG
Tdark
Novelty:  0.73161601
Score:  0.94
Data Source:  STRINGDB
CATSPERB
Tdark
Novelty:  0.69373919
Score:  0.929
Data Source:  STRINGDB
CATSPER1
Tchem
Family:  IC
Novelty:  0.01971564
Score:  0.883
Data Source:  STRINGDB
CATSPERZ
Tdark
Novelty:  0.61619097
Score:  0.864
Data Source:  STRINGDB
CATSPERD
Tdark
Novelty:  0.85066163
Score:  0.819
Data Source:  STRINGDB
CCDC60
Tdark
Novelty:  0.62801145
Score:  0.805
Data Source:  STRINGDB
CATSPER2
Tchem
Family:  IC
Novelty:  0.03701031
Score:  0.795
Data Source:  STRINGDB
DESI2
Tbio
Family:  Enzyme
Novelty:  0.026329
Score:  0.775
Data Source:  STRINGDB
CACNA1H
Tclin
Family:  IC
Novelty:  0.00342394
Score:  0.732
Data Source:  STRINGDB
FKBP1A
Tclin
Family:  Enzyme
Novelty:  0.00116174
Score:  0.726
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
catsper channel auxiliary subunit epsilon
VGNC:4978
457866
Macaque
catsper channel auxiliary subunit epsilon
704627
Dog
catsper channel auxiliary subunit epsilon
VGNC:38749
611754
Horse
catsper channel auxiliary subunit epsilon
VGNC:16085
100062241
Cow
catsper channel auxiliary subunit epsilon [Source:HGNC Symbol;Acc:HGNC:28491]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
catsper channel auxiliary subunit epsilon
Macaque
catsper channel auxiliary subunit epsilon
Dog
catsper channel auxiliary subunit epsilon
Horse
catsper channel auxiliary subunit epsilon
Cow
catsper channel auxiliary subunit epsilon [Source:HGNC Symbol;Acc:HGNC:28491]
Publication Statistics
PubMed Score 1.10
PubMed score by year
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Related Publications
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PMID
Year
Title