CARD11
Caspase recruitment domain-containing protein 11
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.9 | ||
cell type or tissue | 0.78 | ||
kinase | 0.72 | ||
tissue sample | 0.63 | ||
biological term | 0.58 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of NF-kappaB in B cells | ||||
Reactome | Adaptive Immune System | ||||
Reactome | C-type lectin receptors (CLRs) | ||||
Reactome | CLEC7A (Dectin-1) signaling | ||||
Reactome | Downstream TCR signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of NF-kappaB in B cells | ||||
Adaptive Immune System | ||||
C-type lectin receptors (CLRs) | ||||
CLEC7A (Dectin-1) signaling | ||||
Downstream TCR signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 8 | 9 | 97.2 | |||||
eosinophil count | 3 | 4 | 5 | 90.2 | |||||
BMI-adjusted waist circumference | 2 | 5 | 5 | 81.1 | |||||
platelet count | 2 | 2 | 2 | 75.4 | |||||
2 | 2 | 0 | 1.1 | 70.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 9 | 97.2 | |||||
eosinophil count | 5 | 90.2 | |||||
BMI-adjusted waist circumference | 5 | 81.1 | |||||
platelet count | 2 | 75.4 | |||||
0 | 1.1 | 70.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | caspase recruitment domain family member 11 | VGNC:4292 | 463235 | |||||
Mouse | MGI:1916978 | 108723 | ||||||
Dog | caspase recruitment domain family member 11 | VGNC:38714 | 489887 | |||||
Horse | caspase recruitment domain family member 11 | VGNC:16053 | 100058981 | |||||
Cow | caspase recruitment domain family member 11 | VGNC:26761 | 515377 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | caspase recruitment domain family member 11 | |||||
Mouse | ||||||
Dog | caspase recruitment domain family member 11 | |||||
Horse | caspase recruitment domain family member 11 | |||||
Cow | caspase recruitment domain family member 11 | |||||
PMID | Year | Title |
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