Protein Summary
This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]
- ENST00000219611
- ENSP00000219611
- ENSG00000103326
- SOLH
- SOLH
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.91 | ||
histone modification site profile | 0.76 | ||
tissue | 0.69 | ||
cell type or tissue | 0.67 | ||
tissue sample | 0.66 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 98.02 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 69 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 98.02 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 69 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (62)
HERPUD1
Novelty: 0.00793854
p_int: 0.999954222
p_ni: 0.000045778
Score: 0.537
Data Source: BioPlex,STRINGDB
CTLA4
Novelty: 0.00012781
p_int: 0.999591501
p_ni: 0.000401878
p_wrong: 0.000006621
Data Source: BioPlex
UNC119
Novelty: 0.00396292
p_int: 0.999476335
p_ni: 0.000517528
p_wrong: 0.000006137
Score: 0.164
Data Source: BioPlex,STRINGDB
FNDC5
Novelty: 0.0015827
p_int: 0.998804046
p_ni: 0.001195954
Score: 0.187
Data Source: BioPlex,STRINGDB
RNF126
Family: Enzyme
Novelty: 0.08123801
p_int: 0.998647221
p_ni: 0.00135277
p_wrong: 8e-9
Score: 0.254
Data Source: BioPlex,STRINGDB
FAM189A2
Novelty: 0.41335428
p_int: 0.998527102
p_ni: 0.001472875
p_wrong: 2.3e-8
Data Source: BioPlex
CDH5
Novelty: 0.00072649
p_int: 0.991171742
p_ni: 0.008788144
p_wrong: 0.000040113
Score: 0.178
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (2)
Reactome (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Degradation of the extracellular matrix | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Degradation of the extracellular matrix | ||||
Extracellular matrix organization | ||||
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (5)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (12)
Items per page:
1 – 5 of 12
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular volume | 2 | 2 | 2 | 92.8 | |||||
platelet count | 2 | 2 | 2 | 90.6 | |||||
reticulocyte measurement | 2 | 2 | 2 | 85.8 | |||||
mean reticulocyte volume | 1 | 2 | 2 | 81.8 | |||||
reticulocyte count | 2 | 1 | 2 | 76.1 | |||||
Items per page:
1 – 5 of 12
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular volume | 2 | 92.8 | |||||
platelet count | 2 | 90.6 | |||||
reticulocyte measurement | 2 | 85.8 | |||||
mean reticulocyte volume | 2 | 81.8 | |||||
reticulocyte count | 2 | 76.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | calpain 15 | 695881 | ||||||
Mouse | MGI:1355075 | 50817 | ||||||
Rat | RGD:1306514 | 303000 | ||||||
Dog | calpain 15 | VGNC:38703 | 490097 | |||||
Horse | calpain 15 [Source:HGNC Symbol;Acc:HGNC:11182] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | calpain 15 | |||||
Mouse | ||||||
Rat | ||||||
Dog | calpain 15 | |||||
Horse | calpain 15 [Source:HGNC Symbol;Acc:HGNC:11182] | |||||
Publication Statistics
PubMed Score 98.02
PubMed score by year
PubTator Score 5.33
PubTator score by year
Related Publications
Text Mined References (9)
Items per page:
0 of 0
PMID | Year | Title |
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