Tbio CAPN15 Calpain-15

Protein Summary

Description

This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O75808
• B1B1M4
• Q2KHS2
• Q8WTY9
• Q9BUW0

Gene Name

• CAPN15

Ensembl ID

• ENST00000219611
• ENSP00000219611
• ENSG00000103326

Symbol

• SOLH
• SOLH

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.91
histone modification site profile	0.76
tissue	0.69
cell type or tissue	0.67
tissue sample	0.66

Protein Classes

PANTHER Classes

Protein / Hydrolase / Protease / Cysteine Protease / Calpain-15

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Calpain-15

Protein / Calcium-binding Protein / Annexin / Calpain-15

DTO Classes

Protein / Enzyme / Protease / Cysteine Protease / Calpain-15

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 115.26   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 69   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 115.26   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0