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Tbio
CAB39
Calcium-binding protein 39

Protein Summary
Description
Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258418
  • ENSP00000258418
  • ENSG00000135932
  • ENST00000409788
  • ENSP00000386238
  • ENST00000410084
  • ENSP00000386642

Symbol
  • MO25
  • MO25
  • CGI-66
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.96
interacting protein
0.92
biological process
0.85
transcription factor binding site profile
0.82
microRNA
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.5   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 126   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.5   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 126   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0