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Tdark
C9orf40
Uncharacterized protein C9orf40

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376854
  • ENSP00000366050
  • ENSG00000135045
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
EPDR1
Tbio
Novelty:  0.03597825
p_int:  0.999979353
p_ni:  0.000020647
Data Source:  BioPlex
PLPPR2
Tdark
Family:  Enzyme
Novelty:  1.03318406
p_int:  0.999932539
p_ni:  0.000067458
p_wrong:  3e-9
Score:  0.189
Data Source:  BioPlex,STRINGDB
LONRF2
Tdark
Family:  Enzyme
Novelty:  1.01811251
p_int:  0.999874326
p_ni:  0.000122943
p_wrong:  0.000002731
Data Source:  BioPlex
PLOD1
Tbio
Family:  Enzyme
Novelty:  0.00905345
p_int:  0.999807146
p_ni:  0.000192852
p_wrong:  2e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
DNAJB8
Tbio
Novelty:  0.0791748
p_int:  0.99850505
p_ni:  0.001490809
p_wrong:  0.000004141
Score:  0.28
Data Source:  BioPlex,STRINGDB
CALML3
Tbio
Novelty:  0.0336689
p_int:  0.998346273
p_ni:  0.000540872
p_wrong:  0.001112855
Data Source:  BioPlex
GLB1
Tchem
Family:  Enzyme
Novelty:  0.00241713
p_int:  0.987273734
p_ni:  0.012726266
Data Source:  BioPlex
MGRN1
Tbio
Family:  Enzyme
Novelty:  0.04981605
p_int:  0.982554793
p_ni:  0.015810027
p_wrong:  0.001635181
Score:  0.241
Data Source:  BioPlex,STRINGDB
CTSA
Tchem
Family:  Enzyme
Novelty:  0.00170931
p_int:  0.946215996
p_ni:  0.053784004
Data Source:  BioPlex
TCEAL1
Tbio
Novelty:  0.02210924
p_int:  0.920449706
p_ni:  0.000945409
p_wrong:  0.078604885
Score:  0.173
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
magnesium measurement
2
2
1
5.3
84.3
calcium measurement
2
2
2
81.2
magnesium:creatinine ratio measurement
1
1
1
79.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
magnesium measurement
1
5.3
84.3
calcium measurement
2
81.2
magnesium:creatinine ratio measurement
1
79.6
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 9 C9orf40 homolog
VGNC:14379
464530
Macaque
chromosome 15 open reading frame, human C9orf40
703542
Mouse
MGI:3583960
225995
Rat
RGD:1563237
499331
Dog
chromosome 1 C9orf40 homolog
VGNC:52511
608611
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 9 C9orf40 homolog
Macaque
chromosome 15 open reading frame, human C9orf40
Mouse
Rat
Dog
chromosome 1 C9orf40 homolog
Publication Statistics
PubMed Score 0.46
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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PMID
Year
Title