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Tdark
TEX22
Testis-expressed protein 22

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000451127
  • ENSP00000397002
  • ENSG00000226174
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
gene perturbation
0.88
tissue
0.62
cell line
0.55
cellular component
0.5


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.24   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.24   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum non-albumin protein measurement
1
4
4
97.2
heel bone mineral density
2
2
2
72.8
blood protein measurement
1
2
2
71.8
sex hormone-binding globulin measurement
1
1
1
42.3
serum IgG glycosylation measurement
1
1
1
39.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum non-albumin protein measurement
4
97.2
heel bone mineral density
2
72.8
blood protein measurement
2
71.8
sex hormone-binding globulin measurement
1
42.3
serum IgG glycosylation measurement
1
39.5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-C9J3V5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (14)
1 – 10 of 14
PSMG3
Tchem
Novelty:  0.01730294
Score:  0.673
Data Source:  STRINGDB
BTBD6
Tdark
Novelty:  0.24005804
Score:  0.654
Data Source:  STRINGDB
OR8H3
Tdark
Family:  oGPCR
Novelty:  52
Score:  0.63
Data Source:  STRINGDB
NUDT14
Tbio
Family:  Enzyme
Novelty:  0.11929401
Score:  0.589
Data Source:  STRINGDB
TMEM121
Tdark
Novelty:  0.18541234
Score:  0.571
Data Source:  STRINGDB
FAM221A
Tdark
Novelty:  1.40181414
Score:  0.471
Data Source:  STRINGDB
PACS2
Tbio
Novelty:  0.00887813
Score:  0.471
Data Source:  STRINGDB
FAM120C
Tbio
Novelty:  0.03333181
Score:  0.457
Data Source:  STRINGDB
MTHFD2L
Tdark
Family:  Enzyme
Novelty:  0.18530504
Score:  0.454
Data Source:  STRINGDB
AGBL3
Tbio
Family:  Enzyme
Novelty:  0.01634546
Score:  0.452
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.24

PubMed score by year
PubTator Score  0.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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