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Tdark
C6orf48
Protein G8

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375639
  • ENSP00000364790
  • ENSG00000204387
  • ENST00000614363
  • ENSP00000480389

Symbol
  • G8
  • G8
  • D6S57
  • C6orf48
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 171.52   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 171.52   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (17)
BAG6
Tbio
Novelty:  0.0035578
Score:  0.839
Data Source:  STRINGDB
KIR2DL4
Tbio
Novelty:  0.00163053
Score:  0.796
Data Source:  STRINGDB
MRPL58
Tbio
Family:  Enzyme
Novelty:  0.00178011
Score:  0.793
Data Source:  STRINGDB
SPECC1
Tbio
Novelty:  0.00830299
Score:  0.789
Data Source:  STRINGDB
PRSS57
Tbio
Family:  Enzyme
Novelty:  0.00250647
Score:  0.787
Data Source:  STRINGDB
CLIC1
Tbio
Family:  IC
Novelty:  0.00622691
Score:  0.764
Data Source:  STRINGDB
SH2D3A
Tbio
Novelty:  0.00185943
Score:  0.732
Data Source:  STRINGDB
SH2D3C
Tbio
Novelty:  0.00356605
Score:  0.709
Data Source:  STRINGDB
PPT2
Tbio
Family:  Enzyme
Novelty:  0.00829249
Score:  0.642
Data Source:  STRINGDB
HGS
Tbio
Family:  Enzyme
Novelty:  0.00665044
Score:  0.63
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (69)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
5
15
19
97.9
3
3
0
2.3
96
BMI-adjusted hip circumference
2
12
13
95.2
waist-hip ratio
2
15
17
94.5
waist circumference
2
11
12
94
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
19
97.9
0
2.3
96
BMI-adjusted hip circumference
13
95.2
waist-hip ratio
17
94.5
waist circumference
12
94
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 171.52
PubMed score by year
PubTator Score 52.92
PubTator score by year
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Related Publications
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PMID
Year
Title