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Tdark
C5orf34
Uncharacterized protein C5orf34

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306862
  • ENSP00000303490
  • ENSG00000172244
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.41   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.41   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
BBS7
Tbio
Novelty:  0.03611111
p_int:  0.998254462
p_ni:  0.00173916
p_wrong:  0.000006377
Data Source:  BioPlex
THBS3
Tbio
Novelty:  0.01915634
p_int:  0.997516702
p_ni:  0.002480588
p_wrong:  0.00000271
Score:  0.183
Data Source:  BioPlex,STRINGDB
DNAJC7
Tbio
Novelty:  0.02133191
p_int:  0.994410052
p_ni:  0.005589948
Data Source:  BioPlex
IL17RA
Tclin
Novelty:  0.00416706
p_int:  0.993914045
p_ni:  0.006078967
p_wrong:  0.000006988
Data Source:  BioPlex
CRYL1
Tbio
Family:  Enzyme
Novelty:  0.04513297
p_int:  0.984008009
p_ni:  0.015991985
p_wrong:  6e-9
Data Source:  BioPlex
DOCK5
Tbio
Novelty:  0.03153692
p_int:  0.981406651
p_ni:  0.018593324
p_wrong:  2.5e-8
Data Source:  BioPlex
RCCD1
Tbio
Novelty:  0.07481641
p_int:  0.972807099
p_ni:  0.027115462
p_wrong:  0.000077439
Data Source:  BioPlex
TKT
Tchem
Family:  Enzyme
Novelty:  0.00333936
p_int:  0.967938691
p_ni:  0.032061309
Data Source:  BioPlex
IQCF1
Tdark
Novelty:  0.78525464
p_int:  0.953112095
p_ni:  0.046887856
p_wrong:  4.9e-8
Data Source:  BioPlex
RFXANK
Tbio
Novelty:  0.00355465
p_int:  0.915907431
p_ni:  0.081119465
p_wrong:  0.002973104
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
2
2
68.1
mathematical ability
1
1
1
57.3
lymphocyte count
1
1
1
57.3
leukocyte count
1
1
1
35
self reported educational attainment
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
68.1
mathematical ability
1
57.3
lymphocyte count
1
57.3
leukocyte count
1
35
self reported educational attainment
1
33.1
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 5 C5orf34 homolog
VGNC:3917
735815
Macaque
chromosome 6 open reading frame, human C5orf34
700618
Mouse
MGI:1914642
67392
Rat
RGD:1306227
310377
Dog
chromosome 4 C5orf34 homolog
VGNC:49203
612464
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 5 C5orf34 homolog
Macaque
chromosome 6 open reading frame, human C5orf34
Mouse
Rat
Dog
chromosome 4 C5orf34 homolog
Publication Statistics
PubMed Score 1.41
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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PMID
Year
Title