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Tdark
C5orf30
UNC119-binding protein C5orf30

Protein Summary
Description
Probably plays a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B (PubMed:22085962). May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells (PubMed:22085962).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319933
  • ENSP00000326110
  • ENSG00000181751
  • ENST00000510890
  • ENSP00000421270
  • ENST00000515669
  • ENSP00000422836
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.24   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.24   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
UNC119
Tchem
Novelty:  0.00396292
p_int:  0.999999955
p_ni:  4.4e-8
p_wrong:  2e-9
Score:  0.738
Data Source:  BioPlex,STRINGDB
AVPI1
Tbio
Novelty:  0.28472403
p_int:  0.999999645
p_ni:  3.32e-7
p_wrong:  2.3e-8
Data Source:  BioPlex
STK16
Tchem
Family:  Kinase
Novelty:  0.01499094
p_int:  0.999998445
p_ni:  0.00000137
p_wrong:  1.85e-7
Score:  0.239
Data Source:  BioPlex,STRINGDB
LRRC57
Tdark
Novelty:  5.85929893
p_int:  0.999994915
p_ni:  0.000005085
Score:  0.309
Data Source:  BioPlex,STRINGDB
SPDEF
Tbio
Family:  TF
Novelty:  0.00618802
p_int:  0.999990514
p_ni:  0.000009478
p_wrong:  9e-9
Score:  0.834
Data Source:  BioPlex,STRINGDB
RSPRY1
Tdark
Novelty:  0.26883105
p_int:  0.999988724
p_ni:  0.000011045
p_wrong:  2.31e-7
Score:  0.313
Data Source:  BioPlex,STRINGDB
NUSAP1
Tbio
Novelty:  0.01702118
p_int:  0.999985526
p_ni:  0.000014468
p_wrong:  6e-9
Score:  0.234
Data Source:  BioPlex,STRINGDB
ANKRD55
Tbio
Novelty:  0.09730833
Score:  0.669
Data Source:  STRINGDB
SMIM21
Tdark
Novelty:  1.27326849
Score:  0.586
Data Source:  STRINGDB
GIN1
Tbio
Family:  Enzyme
Novelty:  0.0247804
Score:  0.57
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (25)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
2
2
1.1
82.9
mean corpuscular hemoglobin concentration
1
1
1
68
intelligence
3
3
3
5.7
66
worry measurement
2
3
2
6.4
63.7
risk-taking behaviour
2
2
2
62.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1.1
82.9
mean corpuscular hemoglobin concentration
1
68
intelligence
3
5.7
66
worry measurement
2
6.4
63.7
risk-taking behaviour
2
62.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
chromosome 6 open reading frame, human C5orf30
703692
Mouse
MGI:1277184
52392
Rat
RGD:1562136
501195
Dog
chromosome 3 C5orf30 homolog
VGNC:52562
608661
Horse
chromosome 14 C5orf30 homolog
VGNC:49243
100064702
Species
Name
OMA
EggNOG
Inparanoid
Macaque
chromosome 6 open reading frame, human C5orf30
Mouse
Rat
Dog
chromosome 3 C5orf30 homolog
Horse
chromosome 14 C5orf30 homolog
Publication Statistics
PubMed Score 6.24
PubMed score by year
PubTator Score 3.54
PubTator score by year
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Related Publications
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PMID
Year
Title