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Tdark
C5orf22
UPF0489 protein C5orf22

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.75   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.75   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
SURF2
Tdark
Novelty:  0.10662558
p_int:  0.999997032
p_ni:  0.000001284
p_wrong:  0.000001684
Score:  0.207
Data Source:  BioPlex,STRINGDB
WBP11
Tbio
Novelty:  0.03891455
p_int:  0.999993444
p_ni:  0.000006556
Score:  0.332
Data Source:  BioPlex,STRINGDB
SPON1
Tbio
Novelty:  0.01071398
p_int:  0.999989044
p_ni:  0.000010757
p_wrong:  2e-7
Data Source:  BioPlex
OSM
Tbio
Novelty:  0.00227405
p_int:  0.99993194
p_ni:  0.000040495
p_wrong:  0.000027566
Score:  0.534
Data Source:  BioPlex,STRINGDB
CTAG2
Tbio
Novelty:  0.02983879
p_int:  0.975791352
p_ni:  0.00093728
p_wrong:  0.023271369
Data Source:  BioPlex
DEF8
Tdark
Novelty:  0.21146806
p_int:  0.968035472
p_ni:  0.000509981
p_wrong:  0.031454547
Score:  0.239
Data Source:  BioPlex,STRINGDB
C1orf109
Tdark
Novelty:  0.93042195
Score:  0.805
Data Source:  STRINGDB
TRMT13
Tdark
Novelty:  3.91234304
Score:  0.753
Data Source:  STRINGDB
SAYSD1
Tdark
Novelty:  0.62764863
Score:  0.734
Data Source:  STRINGDB
CALHM4
Tdark
Family:  IC
Novelty:  2.79788039
Score:  0.723
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
17.8
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 5 C5orf22 homolog
VGNC:3913
461936
Macaque
chromosome 6 open reading frame, human C5orf22
695901
Mouse
MGI:1925127
77877
Rat
RGD:1306502
310158
Dog
chromosome 4 C5orf22 homolog
VGNC:49202
612640
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 5 C5orf22 homolog
Macaque
chromosome 6 open reading frame, human C5orf22
Mouse
Rat
Dog
chromosome 4 C5orf22 homolog
Publication Statistics
PubMed Score 0.75
PubMed score by year
PubTator Score 0.33
PubTator score by year
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Related Publications
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PMID
Year
Title