C4BPA
C4b-binding protein alpha chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.65 | ||
biological term | 0.58 | ||
cell line | 0.52 | ||
small molecule perturbation | 0.51 | ||
virus perturbation | 0.5 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Complement cascade | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Regulation of Complement cascade | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Complement cascade | ||||
Immune System | ||||
Innate Immune System | ||||
Regulation of Complement cascade | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 3 | 3 | 91.7 | |||||
glomerular filtration rate | 2 | 2 | 2 | 75.4 | |||||
creatinine measurement | 1 | 1 | 1 | 62.6 | |||||
diastolic blood pressure | 1 | 1 | 1 | 49.5 | |||||
3 | 1 | 1 | 1.1 | 45.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 91.7 | |||||
glomerular filtration rate | 2 | 75.4 | |||||
creatinine measurement | 1 | 62.6 | |||||
diastolic blood pressure | 1 | 49.5 | |||||
1 | 1.1 | 45.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | complement component 4 binding protein alpha | VGNC:8241 | 457688 | |||||
Macaque | C4b-binding protein alpha chain | 693382 | ||||||
Mouse | MGI:104965 | 22789 | ||||||
Rat | RGD:2235 | 24235 | ||||||
Dog | complement component 4 binding protein alpha | VGNC:38593 | 100687316 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | complement component 4 binding protein alpha | |||||
Macaque | C4b-binding protein alpha chain | |||||
Mouse | ||||||
Rat | ||||||
Dog | complement component 4 binding protein alpha | |||||
PMID | Year | Title |
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