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Tdark
C2orf54
Uncharacterized protein C2orf54

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.53   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.53   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
NIPSNAP3A
Tdark
Novelty:  0.45687717
p_int:  0.994371488
p_ni:  0.005628426
p_wrong:  8.6e-8
Score:  0.39
Data Source:  BioPlex,STRINGDB
THAP4
Tbio
Family:  TF
Novelty:  0.19820029
Score:  0.707
Data Source:  STRINGDB
ANKMY1
Tbio
Novelty:  0.15068511
Score:  0.697
Data Source:  STRINGDB
DTYMK
Tbio
Family:  Kinase
Novelty:  0.00746576
Score:  0.648
Data Source:  STRINGDB
ANO7
Tbio
Novelty:  0.06494594
Score:  0.631
Data Source:  STRINGDB
MYCBP2
Tbio
Family:  Enzyme
Novelty:  0.00413684
Score:  0.629
Data Source:  STRINGDB
SNED1
Tbio
Novelty:  0.00936803
Score:  0.625
Data Source:  STRINGDB
SEPT2
Tbio
Novelty:  0.01047916
Score:  0.616
Data Source:  STRINGDB
FARP2
Tbio
Novelty:  0.09590913
Score:  0.611
Data Source:  STRINGDB
STK25
Tchem
Family:  Kinase
Novelty:  0.03229688
Score:  0.6
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
1
1
1
79.6
BMI-adjusted hip circumference
3
5
6
64.4
body height
2
2
2
55.5
vital capacity
1
1
1
21.6
sex hormone-binding globulin measurement
1
1
1
19
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
1
79.6
BMI-adjusted hip circumference
6
64.4
body height
2
55.5
vital capacity
1
21.6
sex hormone-binding globulin measurement
1
19
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 2B open reading frame, human C2orf54
743645
Mouse
MGI:1919124
71874
Rat
RGD:1563692
501185
Dog
uncharacterized protein C2orf54
100855821
Dog
uncharacterized protein C2orf54-like
609000
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 2B open reading frame, human C2orf54
Mouse
Rat
Dog
uncharacterized protein C2orf54
Dog
uncharacterized protein C2orf54-like
Publication Statistics
PubMed Score 0.53
PubMed score by year
PubTator Score 0.09
PubTator score by year
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Related Publications
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PMID
Year
Title