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Tdark
C1orf74
UPF0739 protein C1orf74

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294811
  • ENSP00000294811
  • ENSG00000162757

Symbol
  • URLC4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (13)
BBOF1
Tdark
Novelty:  0.82370886
Score:  0.646
Data Source:  STRINGDB
RHEX
Tbio
Novelty:  0.20957256
Score:  0.632
Data Source:  STRINGDB
TRAF3IP3
Tbio
Novelty:  0.12180834
Score:  0.542
Data Source:  STRINGDB
EIF2D
Tbio
Novelty:  0.03765592
Score:  0.528
Data Source:  STRINGDB
SARG
Tbio
Novelty:  0.05063046
Score:  0.491
Data Source:  STRINGDB
FAM72A
Tbio
Novelty:  0.02842806
Score:  0.479
Data Source:  STRINGDB
DIEXF
Tbio
Novelty:  0.05892659
Score:  0.474
Data Source:  STRINGDB
YOD1
Tbio
Family:  Enzyme
Novelty:  0.05709057
Score:  0.44
Data Source:  STRINGDB
G0S2
Tbio
Novelty:  0.02273959
Score:  0.424
Data Source:  STRINGDB
AZIN1
Tbio
Family:  Enzyme
Novelty:  0.03017595
Score:  0.42
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
6
7
0
1.7
97.7
Cleft palate
4
5
0
1.5
93.6
Oral cleft
2
3
1
1.6
86.5
mean corpuscular hemoglobin concentration
1
1
1
72.6
mean corpuscular volume
1
1
1
66.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.7
97.7
Cleft palate
0
1.5
93.6
Oral cleft
1
1.6
86.5
mean corpuscular hemoglobin concentration
1
72.6
mean corpuscular volume
1
66.3
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf74 homolog
VGNC:4993
457700
Mouse
MGI:2441776
319266
Rat
RGD:1642423
100125367
Dog
chromosome 7 C1orf74 homolog
VGNC:52588
100687793
Horse
chromosome 5 C1orf74 homolog
VGNC:52337
100056345
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf74 homolog
Mouse
Rat
Dog
chromosome 7 C1orf74 homolog
Horse
chromosome 5 C1orf74 homolog
Publication Statistics
PubMed Score 0.16
PubMed score by year
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Related Publications
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PMID
Year
Title