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Tbio
C1orf43
Uncharacterized protein C1orf43

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000350592
  • ENSP00000271925
  • ENSG00000143612
  • ENST00000362076
  • ENSP00000354496
  • ENST00000368518
  • ENSP00000357504
  • ENST00000368521
  • ENSP00000357507

Symbol
  • NICE3
  • NS5ATP4
  • NICE3
  • NICE-3
  • S863-3
  • HSPC012
  • NS5ATP4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.82   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 66   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.82   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 66   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (53)
CCDC28A
Tdark
Novelty:  0.47441753
p_int:  0.999442952
p_ni:  0.000557048
p_wrong:  1e-9
Data Source:  BioPlex
KCNS3
Tclin
Family:  IC
Novelty:  0.05882087
p_int:  0.999056394
p_ni:  0.000943606
Data Source:  BioPlex
CNGA3
Tchem
Family:  IC
Novelty:  0.00818181
p_int:  0.99903629
p_ni:  0.000963708
p_wrong:  2e-9
Data Source:  BioPlex
CHRNB1
Tclin
Family:  IC
Novelty:  0.04777051
p_int:  0.998908546
p_ni:  0.001091453
p_wrong:  1e-9
Data Source:  BioPlex
ZNRF4
Tbio
Novelty:  0.16505328
p_int:  0.99825633
p_ni:  0.00174367
Data Source:  BioPlex
PCDHB7
Tdark
Novelty:  0.60789936
p_int:  0.997861535
p_ni:  0.002138465
Data Source:  BioPlex
NKAIN1
Tdark
Family:  Enzyme
Novelty:  0.52190272
p_int:  0.997782995
p_ni:  0.002217005
Data Source:  BioPlex
SLC39A4
Tbio
Family:  Transporter
Novelty:  0.00742159
p_int:  0.997659118
p_ni:  0.002340867
p_wrong:  1.5e-8
Data Source:  BioPlex
TEX264
Tbio
Novelty:  0.32406417
p_int:  0.995729305
p_ni:  0.004270692
p_wrong:  3e-9
Data Source:  BioPlex
TRPV3
Tchem
Family:  IC
Novelty:  0.00533583
p_int:  0.993988711
p_ni:  0.006011281
p_wrong:  8e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-reactive protein measurement
2
5
5
91.4
triglyceride measurement
3
3
3
86.5
mean corpuscular volume
3
3
3
83.9
mathematical ability
2
1
2
77.1
mean platelet volume
3
1
3
74.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-reactive protein measurement
5
91.4
triglyceride measurement
3
86.5
mean corpuscular volume
3
83.9
mathematical ability
2
77.1
mean platelet volume
3
74.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf43 homolog
VGNC:4998
469503
Macaque
chromosome 1 open reading frame, human C1orf43
716453
Mouse
MGI:1914027
99650
Rat
RGD:1359625
361985
Dog
chromosome 1 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:29876]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf43 homolog
Macaque
chromosome 1 open reading frame, human C1orf43
Mouse
Rat
Dog
chromosome 1 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:29876]
Publication Statistics
PubMed Score 6.82
PubMed score by year
PubTator Score 2.35
PubTator score by year
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Related Publications
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PMID
Year
Title