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Tdark
C1orf112
Uncharacterized protein C1orf112

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.04   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.04   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (79)
CD83
Tbio
Novelty:  0.00138653
p_int:  0.997926573
p_ni:  0.002073427
Data Source:  BioPlex
OPALIN
Tdark
Novelty:  0.08221612
p_int:  0.994376936
p_ni:  0.00562304
p_wrong:  2.4e-8
Data Source:  BioPlex
EDNRB
Tclin
Family:  GPCR
Novelty:  0.00053875
p_int:  0.989190177
p_ni:  0.010805976
p_wrong:  0.000003847
Data Source:  BioPlex
CLEC4A
Tbio
Novelty:  0.01821643
p_int:  0.98913752
p_ni:  0.010862477
p_wrong:  3e-9
Data Source:  BioPlex
OPRM1
Tclin
Family:  GPCR
Novelty:  0.0003701
p_int:  0.975855822
p_ni:  0.024144174
p_wrong:  3e-9
Data Source:  BioPlex
C5AR2
Tbio
Family:  GPCR
Novelty:  0.01193736
p_int:  0.961766527
p_ni:  0.038233473
Data Source:  BioPlex
SPINT2
Tbio
Family:  Enzyme
Novelty:  0.0046602
p_int:  0.959751194
p_ni:  0.040247604
p_wrong:  0.000001202
Data Source:  BioPlex
CCR6
Tchem
Family:  GPCR
Novelty:  0.00257933
p_int:  0.954772397
p_ni:  0.045178853
p_wrong:  0.00004875
Data Source:  BioPlex
P01889
Tbio
Novelty:  0.00790207
p_int:  0.927441861
p_ni:  0.071827936
p_wrong:  0.000730203
Data Source:  BioPlex
FCGRT
Tclin
Novelty:  0.00105713
p_int:  0.923180117
p_ni:  0.076819751
p_wrong:  1.32e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
adhesion molecule measurement
1
2
0
14.9
93.7
1
2
2
88.5
e-selectin measurement
1
1
1
82.2
monocyte count
1
1
1
78.3
myeloid white cell count
2
2
2
77.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
adhesion molecule measurement
0
14.9
93.7
2
88.5
e-selectin measurement
1
82.2
monocyte count
1
78.3
myeloid white cell count
2
77.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf112 homolog
VGNC:4981
457501
Macaque
chromosome 1 open reading frame, human C1orf112
701646
Mouse
MGI:3590554
381306
Rat
RGD:1563470
498265
Dog
chromosome 7 C1orf112 homolog
VGNC:52585
611419
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf112 homolog
Macaque
chromosome 1 open reading frame, human C1orf112
Mouse
Rat
Dog
chromosome 7 C1orf112 homolog
Publication Statistics
PubMed Score 2.04
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
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PMID
Year
Title