You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
C1orf109
Uncharacterized protein C1orf109

Protein Summary
Description
May promote cancer cell proliferation by controlling the G1 to S phase transition.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358011
  • ENSP00000350704
  • ENSG00000116922
  • ENST00000464085
  • ENSP00000477159
  • ENST00000494120
  • ENSP00000477273
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.36   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 45   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.36   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 45   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
CINP
Tbio
Family:  Enzyme
Novelty:  0.07004715
p_int:  0.999999999
p_ni:  1e-9
Score:  0.83
Data Source:  BioPlex,STRINGDB
SPATA5L1
Tdark
Family:  Enzyme
Novelty:  0.5393372
p_int:  0.998423756
p_ni:  0.000004463
p_wrong:  0.001571781
Score:  0.874
Data Source:  BioPlex,STRINGDB
CWC25
Tdark
Novelty:  0.13727856
Score:  0.841
Data Source:  STRINGDB
SLCO1A2
Tchem
Family:  Transporter
Novelty:  0.00248357
Score:  0.841
Data Source:  STRINGDB
RUBCNL
Tbio
Novelty:  0.20019585
Score:  0.841
Data Source:  STRINGDB
LIX1
Tbio
Novelty:  0.03028158
Score:  0.841
Data Source:  STRINGDB
PGM2
Tbio
Family:  Enzyme
Novelty:  0.00922421
Score:  0.841
Data Source:  STRINGDB
CALHM4
Tdark
Family:  IC
Novelty:  2.79788039
Score:  0.841
Data Source:  STRINGDB
RDH13
Tbio
Family:  Enzyme
Novelty:  0.20184998
Score:  0.841
Data Source:  STRINGDB
ACOT11
Tbio
Family:  Enzyme
Novelty:  0.0400726
Score:  0.841
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
corneal topography
4
1
4
87.2
intraocular pressure measurement
2
1
2
53.3
mathematical ability
3
2
3
53.2
1
1
0
1.1
50.6
1
1
0
1.1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
corneal topography
4
87.2
intraocular pressure measurement
2
53.3
mathematical ability
3
53.2
0
1.1
50.6
0
1.1
35
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf109 homolog
VGNC:4979
456761
Rat
RGD:1560436
500546
Dog
chromosome 15 C1orf109 homolog
VGNC:52497
608173
Horse
chromosome 2 C1orf109 homolog
VGNC:50651
100054694
Cow
chromosome 3 C1orf109 homolog
VGNC:52706
508021
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 1 C1orf109 homolog
Rat
Dog
chromosome 15 C1orf109 homolog
Horse
chromosome 2 C1orf109 homolog
Cow
chromosome 3 C1orf109 homolog
Publication Statistics
PubMed Score 1.36
PubMed score by year
PubTator Score 1.05
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title