You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
C1QTNF9B
Complement C1q and tumor necrosis factor-related protein 9B

Protein Summary
Description
Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382137
  • ENSP00000371572
  • ENSG00000205863
  • ENST00000382140
  • ENSP00000371575

Symbol
  • CTRP9B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.67
tissue
0.56
tissue sample
0.51
protein domain
0.41
cell line
0.36


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.32   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.32   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
C1QTNF9
Tbio
Novelty:  0.03485116
p_int:  1
Score:  0.398
Data Source:  BioPlex,STRINGDB
INHBE
Tbio
Novelty:  0.07526145
p_int:  0.999748986
p_ni:  0.000247321
p_wrong:  0.000003693
Data Source:  BioPlex
COL14A1
Tbio
Novelty:  0.01760399
p_int:  0.998197391
p_ni:  0.001802608
p_wrong:  1e-9
Data Source:  BioPlex
COL2A1
Tbio
Novelty:  0.0011102
p_int:  0.98787528
p_ni:  0.012105967
p_wrong:  0.000018754
Score:  0.164
Data Source:  BioPlex,STRINGDB
SERPINE2
Tbio
Novelty:  0.00246375
p_int:  0.982315566
p_ni:  0.017636276
p_wrong:  0.000048158
Data Source:  BioPlex
CTSF
Tchem
Family:  Enzyme
Novelty:  0.01359417
p_int:  0.982090823
p_ni:  0.017422153
p_wrong:  0.000487023
Data Source:  BioPlex
P3H3
Tbio
Family:  Enzyme
Novelty:  0.0010004
p_int:  0.973747059
p_ni:  0.026252941
Data Source:  BioPlex
COLGALT2
Tbio
Family:  Enzyme
Novelty:  0.15981994
p_int:  0.970885926
p_ni:  0.029113472
p_wrong:  6.02e-7
Data Source:  BioPlex
CEMIP2
Tbio
Novelty:  0.04698236
p_int:  0.970317094
p_ni:  0.02764691
p_wrong:  0.002035996
Data Source:  BioPlex
UBE3D
Tbio
Family:  Enzyme
Novelty:  0.44919491
p_int:  0.959703544
p_ni:  0.021662724
p_wrong:  0.018633731
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.3
66.8
tumor necrosis factor receptor II measurement
1
1
0
15.5
0.7
fatty acid measurement
1
1
0
15.5
0.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
66.8
tumor necrosis factor receptor II measurement
0
15.5
0.7
fatty acid measurement
0
15.5
0.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3045252
239126
Rat
RGD:1560876
364395
Horse
complement C1q and tumor necrosis factor-related protein 9A
100050508
Cow
C1q and TNF related 9
523616
Pig
complement C1q and tumor necrosis factor-related protein 9
100522569
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
complement C1q and tumor necrosis factor-related protein 9A
Cow
C1q and TNF related 9
Pig
complement C1q and tumor necrosis factor-related protein 9
Publication Statistics
PubMed Score 1.32
PubMed score by year
PubTator Score 0.73
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title