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Tbio
C1QTNF9
Complement C1q and tumor necrosis factor-related protein 9A

Protein Summary
Description
Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000332018
  • ENSP00000333737
  • ENSG00000240654
  • ENST00000382071
  • ENSP00000371503

Symbol
  • C1QTNF9A
  • AQL1
  • CTRP9
  • C1QTNF9A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.64
PubMedID
0.58
tissue
0.52
microRNA
0.45
cell line
0.44


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 61.65   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 61.65   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (25)
C1QTNF9B
Tdark
Novelty:  0.7643008
p_int:  1
Score:  0.398
Data Source:  BioPlex,STRINGDB
PHKA1
Tbio
Family:  Kinase
Novelty:  0.02895127
p_int:  0.999933538
p_ni:  0.000066462
Score:  0.201
Data Source:  BioPlex,STRINGDB
COL14A1
Tbio
Novelty:  0.01760399
p_int:  0.999373681
p_ni:  0.000626319
Data Source:  BioPlex
COL2A1
Tbio
Novelty:  0.0011102
p_int:  0.995800723
p_ni:  0.004175122
p_wrong:  0.000024154
Score:  0.706
Data Source:  BioPlex,STRINGDB
TSNAX
Tbio
Novelty:  0.00888891
p_int:  0.995699704
p_ni:  0.004300295
Score:  0.183
Data Source:  BioPlex,STRINGDB
COL6A2
Tbio
Novelty:  0.01275082
p_int:  0.995644649
p_ni:  0.004355351
Score:  0.194
Data Source:  BioPlex,STRINGDB
C1QL1
Tdark
Novelty:  0.11689088
p_int:  0.980196868
p_ni:  0.019802997
p_wrong:  1.35e-7
Score:  0.302
Data Source:  BioPlex,STRINGDB
DHRS4
Tbio
Family:  Enzyme
Novelty:  0.02992279
p_int:  0.946734856
p_ni:  0.053265143
p_wrong:  1e-9
Data Source:  BioPlex
COLGALT2
Tbio
Family:  Enzyme
Novelty:  0.15981994
p_int:  0.93435727
p_ni:  0.06564273
Score:  0.517
Data Source:  BioPlex,STRINGDB
COL6A1
Tbio
Novelty:  0.00644855
p_int:  0.929528372
p_ni:  0.070471628
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
2
3
89.1
Thyroid preparation use measurement
1
1
1
81.3
autoimmune thyroid disease
1
1
0
1.1
75.7
thyroid stimulating hormone measurement
1
1
1
59.8
mean corpuscular volume
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
89.1
Thyroid preparation use measurement
1
81.3
autoimmune thyroid disease
0
1.1
75.7
thyroid stimulating hormone measurement
1
59.8
mean corpuscular volume
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
complement C1q and tumor necrosis factor-related protein 9A-like
707238
Mouse
MGI:3045252
239126
Rat
RGD:1560876
364395
Dog
C1q and TNF related 9
609026
Horse
complement C1q and tumor necrosis factor-related protein 9A
100050508
Species
Name
OMA
EggNOG
Inparanoid
Macaque
complement C1q and tumor necrosis factor-related protein 9A-like
Mouse
Rat
Dog
C1q and TNF related 9
Horse
complement C1q and tumor necrosis factor-related protein 9A
Publication Statistics
PubMed Score 61.65
PubMed score by year
PubTator Score 20.65
PubTator score by year
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Related Publications
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PMID
Year
Title