Tdark C1QL4 Complement C1q-like protein 4

Protein Summary

Description

May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity).

Uniprot Accession IDs

• Q86Z23

Gene Name

• C1QL4

Ensembl ID

• ENST00000334221
• ENSP00000335285
• ENSG00000186897

Symbol

• CTRP11
• CTRP11
• C1QTNF11

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.59
histone modification site profile	0.58
PubMedID	0.51
transcription factor	0.44
cell line	0.42

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.56   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 63   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.56   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0