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Tdark
C19orf57
Uncharacterized protein C19orf57

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
NCOA1
Tchem
Family:  Epigenetic
Novelty:  0.00344663
p_int:  0.999938025
p_ni:  0.000061947
p_wrong:  2.9e-8
Score:  0.29
Data Source:  BioPlex,STRINGDB
PRCC
Tbio
Novelty:  0.00836323
p_int:  0.99987363
p_ni:  0.000123368
p_wrong:  0.000003002
Score:  0.193
Data Source:  BioPlex,STRINGDB
PPP2R5E
Tbio
Family:  Enzyme
Novelty:  0.05974697
p_int:  0.811583051
p_ni:  0.188409242
p_wrong:  0.000007707
Score:  0.188
Data Source:  BioPlex,STRINGDB
C19orf67
Tdark
Novelty:  27
Score:  0.7
Data Source:  STRINGDB
PODNL1
Tdark
Novelty:  0.88348014
Score:  0.665
Data Source:  STRINGDB
C19orf53
Tdark
Novelty:  0.86529835
Score:  0.647
Data Source:  STRINGDB
MEIOC
Tdark
Novelty:  0.85732988
Score:  0.629
Data Source:  STRINGDB
RAD9B
Tdark
Novelty:  0.38973762
Score:  0.609
Data Source:  STRINGDB
CNTD1
Tbio
Novelty:  0.22055841
Score:  0.6
Data Source:  STRINGDB
ZCWPW1
Tbio
Family:  Epigenetic
Novelty:  0.11264543
Score:  0.582
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
3
3
97
leukocyte count
2
2
2
79.3
myeloid white cell count
1
1
1
77.4
lymphocyte percentage of leukocytes
1
1
1
75.7
neutrophil percentage of leukocytes
1
1
1
75.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
97
leukocyte count
2
79.3
myeloid white cell count
1
77.4
lymphocyte percentage of leukocytes
1
75.7
neutrophil percentage of leukocytes
1
75.4
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 19 C19orf57 homolog
VGNC:3653
455771
Macaque
chromosome 19 open reading frame, human C19orf57
718466
Mouse
MGI:1921916
74666
Rat
RGD:1306072
304654
Dog
chromosome 20 C19orf57 homolog
VGNC:52517
610858
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 19 C19orf57 homolog
Macaque
chromosome 19 open reading frame, human C19orf57
Mouse
Rat
Dog
chromosome 20 C19orf57 homolog
Publication Statistics
PubMed Score 0.94
PubMed score by year
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Related Publications
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PMID
Year
Title