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Tdark
C19orf53
Leydig cell tumor 10 kDa protein homolog

Protein Summary
Description
May have a potential role in hypercalcemia of malignancy.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000588234
  • ENSP00000465432
  • ENSG00000104979

Symbol
  • LYDG10
  • HSPC023
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.34   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 34   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.34   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
MRPL34
Tdark
Novelty:  1.17388411
p_int:  0.935276334
p_ni:  0.064723634
p_wrong:  3.1e-8
Score:  0.424
Data Source:  BioPlex,STRINGDB
C19orf67
Tdark
Novelty:  27
Score:  0.676
Data Source:  STRINGDB
C19orf57
Tdark
Novelty:  1.59437078
Score:  0.647
Data Source:  STRINGDB
CIAO2B
Tbio
Novelty:  0.09725962
Score:  0.639
Data Source:  STRINGDB
NDUFB7
Tclin
Family:  Enzyme
Novelty:  0.14580093
Score:  0.623
Data Source:  STRINGDB
DCAF15
Tdark
Novelty:  0.13476661
Score:  0.611
Data Source:  STRINGDB
PODNL1
Tdark
Novelty:  0.88348014
Score:  0.559
Data Source:  STRINGDB
WDR83OS
Tdark
Novelty:  1.20205602
Score:  0.55
Data Source:  STRINGDB
ZSWIM4
Tdark
Novelty:  0.96500196
Score:  0.539
Data Source:  STRINGDB
ZNHIT1
Tbio
Novelty:  0.00390514
Score:  0.533
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
4
3
4
88.6
leukocyte count
3
3
3
74.1
brain measurement
1
1
0
11.2
69.4
myeloid white cell count
1
1
1
67.8
lymphocyte percentage of leukocytes
1
1
1
66.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
4
88.6
leukocyte count
3
74.1
brain measurement
0
11.2
69.4
myeloid white cell count
1
67.8
lymphocyte percentage of leukocytes
1
66.2
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 19 C19orf53 homolog
VGNC:10901
455769
Mouse
MGI:1289231
101966
Dog
chromosome 20 C19orf53 homolog
VGNC:52516
610870
Horse
chromosome 7 C19orf53 homolog
VGNC:52355
100147574
Cow
chromosome 7 open reading frame, human C19orf53
614800
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 19 C19orf53 homolog
Mouse
Dog
chromosome 20 C19orf53 homolog
Horse
chromosome 7 C19orf53 homolog
Cow
chromosome 7 open reading frame, human C19orf53
Publication Statistics
PubMed Score 1.34
PubMed score by year
PubTator Score 0.17
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title