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Tdark
C19orf25
UPF0449 protein C19orf25

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000436106
  • ENSP00000397394
  • ENSG00000119559
  • ENST00000585675
  • ENSP00000468688
  • ENST00000586564
  • ENSP00000466372
  • ENST00000592872
  • ENSP00000467861
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
RINT1
Tbio
Novelty:  0.04546291
p_int:  0.9999991
p_ni:  9e-7
Score:  0.969
Data Source:  BioPlex,STRINGDB
SCFD2
Tdark
Novelty:  0.38252131
p_int:  0.999785056
p_ni:  0.000214942
p_wrong:  3e-9
Score:  0.865
Data Source:  BioPlex,STRINGDB
SEC22B
Tbio
Novelty:  0.03035448
p_int:  0.964222416
p_ni:  0.035777584
Score:  0.646
Data Source:  BioPlex,STRINGDB
SLC30A4
Tbio
Family:  Transporter
Novelty:  0.02209
p_int:  0.953918431
p_ni:  0.046076507
p_wrong:  0.000005062
Score:  0.167
Data Source:  BioPlex,STRINGDB
BSG
Tbio
Novelty:  0.0010285
p_int:  0.933738417
p_ni:  0.066261382
p_wrong:  2.01e-7
Data Source:  BioPlex
P2RY8
Tbio
Family:  GPCR
Novelty:  0.05574297
p_int:  0.914777739
p_ni:  0.085221235
p_wrong:  0.000001026
Data Source:  BioPlex
APLNR
Tchem
Family:  GPCR
Novelty:  0.00224203
p_int:  0.903985538
p_ni:  0.096008428
p_wrong:  0.000006034
Data Source:  BioPlex
P2RY12
Tclin
Family:  GPCR
Novelty:  0.00035406
p_int:  0.901777428
p_ni:  0.098222572
Data Source:  BioPlex
TMEM206
Tdark
Novelty:  0.17311172
p_int:  0.877318171
p_ni:  0.122681829
Data Source:  BioPlex
USE1
Tbio
Novelty:  0.00904756
p_int:  0.866663507
p_ni:  0.133264421
p_wrong:  0.000072072
Score:  0.727
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
13.5
hemoglobin measurement
1
1
1
13.5
pulse pressure measurement
1
1
1
12.6
Urinary retention
1
1
0
7.8
3.7
response to radiation
1
1
0
7.8
3.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
13.5
hemoglobin measurement
1
13.5
pulse pressure measurement
1
12.6
Urinary retention
0
7.8
3.7
response to radiation
0
7.8
3.7
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1913624
66374
Rat
RGD:1359127
299612
Cow
chromosome 7 C19orf25 homolog
VGNC:52727
508965
Pig
chromosome 2 C19orf25 homolog
100625377
Opossum
chromosome 3 open reading frame, human C19orf25
100020761
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Cow
chromosome 7 C19orf25 homolog
Pig
chromosome 2 C19orf25 homolog
Opossum
chromosome 3 open reading frame, human C19orf25
Publication Statistics
PubMed Score 0.13
PubMed score by year
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Related Publications
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PMID
Year
Title