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Tdark
C18orf21
UPF0711 protein C18orf21

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333234
  • ENSP00000329492
  • ENSG00000141428
  • ENST00000592875
  • ENSP00000465517
  • ENST00000610527
  • ENSP00000480486

Symbol
  • XTP13
  • XTP13
  • HsT3108
  • PNAS-124
  • PNAS-131
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
RPP25
Tbio
Family:  Enzyme
Novelty:  0.07178063
p_int:  0.999999999
p_ni:  1e-9
Score:  0.873
Data Source:  BioPlex,STRINGDB
POP4
Tbio
Family:  Enzyme
Novelty:  0.01072287
p_int:  0.999999999
p_ni:  1e-9
Score:  0.827
Data Source:  BioPlex,STRINGDB
RPP30
Tbio
Family:  Enzyme
Novelty:  0.01375777
p_int:  0.999999422
p_ni:  5.78e-7
Score:  0.836
Data Source:  BioPlex,STRINGDB
RPP40
Tbio
Family:  Enzyme
Novelty:  0.05981624
p_int:  0.999995063
p_ni:  0.000004937
Score:  0.826
Data Source:  BioPlex,STRINGDB
RPP14
Tbio
Family:  Enzyme
Novelty:  0.10813341
p_int:  0.999986681
p_ni:  0.000009127
p_wrong:  0.000004192
Score:  0.855
Data Source:  BioPlex,STRINGDB
NEPRO
Tbio
Novelty:  0.12980261
p_int:  0.999937888
p_ni:  0.000062112
p_wrong:  1e-9
Score:  0.828
Data Source:  BioPlex,STRINGDB
RPP25L
Tdark
Family:  Enzyme
Novelty:  1.39761189
p_int:  0.999929139
p_ni:  0.000070861
Score:  0.816
Data Source:  BioPlex,STRINGDB
POP5
Tbio
Family:  Enzyme
Novelty:  0.02459167
p_int:  0.9998132
p_ni:  0.000071405
p_wrong:  0.000115395
Score:  0.869
Data Source:  BioPlex,STRINGDB
RPP38
Tbio
Family:  Enzyme
Novelty:  0.06387902
p_int:  0.998927545
p_ni:  0.001072454
p_wrong:  1e-9
Score:  0.806
Data Source:  BioPlex,STRINGDB
MECP2
Tchem
Family:  TF
Novelty:  0.00051767
p_int:  0.998597526
p_ni:  0.001088529
p_wrong:  0.000313944
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
1
1
1
57.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
1
57.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 18 C18orf21 homolog
VGNC:5143
735721
Macaque
chromosome 18 open reading frame, human C18orf21
715440
Mouse
MGI:1915296
68046
Rat
RGD:1564673
498830
Dog
chromosome 7 C18orf21 homolog
VGNC:52582
100856500
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 18 C18orf21 homolog
Macaque
chromosome 18 open reading frame, human C18orf21
Mouse
Rat
Dog
chromosome 7 C18orf21 homolog
Publication Statistics
PubMed Score 1.81
PubMed score by year
PubTator Score 1.50
PubTator score by year
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Related Publications
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PMID
Year
Title