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Tbio
C16orf89
UPF0764 protein C16orf89

Protein Summary
Description
This gene is expressed predominantly in the thyroid. Based on expression patterns similar to thyroid transcription factors and proteins, this gene may function in the development and function of the thyroid. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315997
  • ENSP00000324672
  • ENSG00000153446
  • ENST00000472572
  • ENSP00000420566
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.28   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 13   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.28   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 13   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (7)
LCN9
Tdark
Novelty:  0.25490072
Score:  0.554
Data Source:  STRINGDB
TXNDC11
Tbio
Novelty:  0.07135045
Score:  0.511
Data Source:  STRINGDB
GPR171
Tbio
Family:  GPCR
Novelty:  0.29228187
Score:  0.459
Data Source:  STRINGDB
ROPN1
Tbio
Novelty:  0.05375245
Score:  0.442
Data Source:  STRINGDB
SYNE4
Tbio
Novelty:  0.0739848
Score:  0.44
Data Source:  STRINGDB
LOXHD1
Tbio
Family:  Enzyme
Novelty:  0.06557997
Score:  0.43
Data Source:  STRINGDB
LRRN4
Tbio
Novelty:  0.27448639
Score:  0.405
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
2
3
3
87.4
mean platelet volume
3
2
3
85.1
1
1
0
11.7
45.3
platelet count
1
1
1
27.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
3
87.4
mean platelet volume
3
85.1
0
11.7
45.3
platelet count
1
27.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 16 C16orf89 homolog
VGNC:5693
748367
Mouse
MGI:2146559
239691
Rat
RGD:1565166
287059
Dog
chromosome 6 C16orf89 homolog
VGNC:52573
490018
Horse
chromosome 13 C16orf89 homolog
VGNC:51112
100069997
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 16 C16orf89 homolog
Mouse
Rat
Dog
chromosome 6 C16orf89 homolog
Horse
chromosome 13 C16orf89 homolog
Publication Statistics
PubMed Score 1.28
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title