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Tdark
C16orf70
UPF0183 protein C16orf70

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000219139
  • ENSP00000219139
  • ENSG00000125149
  • ENST00000569600
  • ENSP00000455182

Symbol
  • C16orf6
  • LIN10
  • lin-10
  • C16orf6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.23   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 40   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.23   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
WIPI2
Tbio
Novelty:  0.02685992
p_int:  0.999999989
p_ni:  1e-8
p_wrong:  1e-9
Score:  0.246
Data Source:  BioPlex,STRINGDB
MASTL
Tbio
Family:  Kinase
Novelty:  0.01266037
p_int:  0.999999896
p_wrong:  1.04e-7
Score:  0.319
Data Source:  BioPlex,STRINGDB
BCAS3
Tbio
Novelty:  0.0343539
p_int:  0.999995956
p_ni:  0.000004044
Score:  0.824
Data Source:  BioPlex,STRINGDB
ZBTB16
Tbio
Family:  TF
Novelty:  0.0034205
p_int:  0.999942762
p_ni:  0.000003083
p_wrong:  0.000054155
Score:  0.319
Data Source:  BioPlex,STRINGDB
PPFIA1
Tbio
Novelty:  0.01904029
p_int:  0.999670257
p_ni:  0.000329743
Score:  0.158
Data Source:  BioPlex,STRINGDB
POMP
Tbio
Novelty:  0.01885028
p_int:  0.998481078
p_ni:  0.001518921
p_wrong:  1e-9
Score:  0.232
Data Source:  BioPlex,STRINGDB
APPL1
Tbio
Novelty:  0.00973424
p_int:  0.998233981
p_ni:  0.001766019
Score:  0.207
Data Source:  BioPlex,STRINGDB
POF1B
Tbio
Novelty:  0.1232792
p_int:  0.993640749
p_ni:  0.006359251
Data Source:  BioPlex
SERPINB4
Tbio
Novelty:  0.00522283
p_int:  0.992218853
p_ni:  0.007781147
Score:  0.192
Data Source:  BioPlex,STRINGDB
FBXO30
Tdark
Novelty:  0.60394319
p_int:  0.990287107
p_ni:  0.009712893
Score:  0.183
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
4
4
96.2
mean reticulocyte volume
1
4
4
94.2
heel bone mineral density
1
1
1
78.4
balding measurement
1
2
2
66.8
high density lipoprotein cholesterol measurement
2
2
2
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
4
96.2
mean reticulocyte volume
4
94.2
heel bone mineral density
1
78.4
balding measurement
2
66.8
high density lipoprotein cholesterol measurement
2
54.4
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 16 C16orf70 homolog
VGNC:14490
454152
Macaque
chromosome 20 open reading frame, human C16orf70
695885
Mouse
MGI:2443049
234678
Rat
RGD:621098
207123
Dog
chromosome 5 C16orf70 homolog
VGNC:50436
612982
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 16 C16orf70 homolog
Macaque
chromosome 20 open reading frame, human C16orf70
Mouse
Rat
Dog
chromosome 5 C16orf70 homolog
Publication Statistics
PubMed Score 0.23
PubMed score by year
PubTator Score 1.09
PubTator score by year
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Related Publications
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PMID
Year
Title