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Tbio
C15orf41
Uncharacterized protein C15orf41

Protein Summary
Description
This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000338183
  • ENSP00000342433
  • ENSG00000186073
  • ENST00000437989
  • ENSP00000401362
  • ENST00000562877
  • ENSP00000457854
  • ENST00000566621
  • ENSP00000455397
  • ENST00000567389
  • ENSP00000456736
  • ENST00000643785
  • ENSP00000496696

Symbol
  • HH114
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.16   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 123   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.16   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (25)
ASF1A
Tchem
Novelty:  0.02544466
p_int:  0.999999996
p_ni:  1e-9
p_wrong:  3e-9
Score:  0.228
Data Source:  BioPlex,STRINGDB
ASF1B
Tbio
Novelty:  0.05716701
p_int:  0.999999995
p_ni:  2e-9
p_wrong:  3e-9
Score:  0.186
Data Source:  BioPlex,STRINGDB
ZNF609
Tdark
Novelty:  0.06635612
p_int:  0.996151769
p_ni:  0.00384621
p_wrong:  0.000002022
Data Source:  BioPlex
HELZ
Tbio
Family:  Enzyme
Novelty:  0.08786982
p_int:  0.984618768
p_ni:  0.015381232
Data Source:  BioPlex
SPDL1
Tbio
Novelty:  0.01399644
p_int:  0.964215009
p_ni:  0.035784537
p_wrong:  4.54e-7
Data Source:  BioPlex
DNAJC1
Tbio
Family:  TF
Novelty:  0.07277849
p_int:  0.959158759
p_ni:  0.040839601
p_wrong:  0.00000164
Data Source:  BioPlex
ATXN2
Tbio
Novelty:  0.00373116
p_int:  0.945185153
p_ni:  0.054814847
Data Source:  BioPlex
ZNF703
Tbio
Novelty:  0.03956045
p_int:  0.855687036
p_ni:  0.131133043
p_wrong:  0.013179922
Score:  0.186
Data Source:  BioPlex,STRINGDB
C1orf146
Tdark
Novelty:  6.67972686
Score:  0.767
Data Source:  STRINGDB
CDAN1
Tbio
Novelty:  0.00610604
Score:  0.706
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
2
2
68.5
electrocardiography
1
1
35
57.3
mean corpuscular volume
1
1
1
31.3
mean reticulocyte volume
1
1
1
21.5
red blood cell density measurement
1
1
1
11.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
68.5
electrocardiography
35
57.3
mean corpuscular volume
1
31.3
mean reticulocyte volume
1
21.5
red blood cell density measurement
1
11.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 15 C15orf41 homolog
VGNC:3578
453311
Mouse
MGI:3026886
399568
Rat
RGD:1563680
499864
Dog
chromosome 30 C15orf41 homolog
VGNC:52550
607958
Horse
chromosome 1 C15orf41 homolog
VGNC:50580
100057596
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 15 C15orf41 homolog
Mouse
Rat
Dog
chromosome 30 C15orf41 homolog
Horse
chromosome 1 C15orf41 homolog
Publication Statistics
PubMed Score 9.16
PubMed score by year
PubTator Score 3.98
PubTator score by year
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Related Publications
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PMID
Year
Title