You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
C11orf54
Ester hydrolase C11orf54

Protein Summary
Description
Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000331239
  • ENSP00000331209
  • ENSG00000182919
  • ENST00000354421
  • ENSP00000346403
  • ENST00000528099
  • ENSP00000435113
  • ENST00000528288
  • ENSP00000433721
  • ENST00000540113
  • ENSP00000442094

Symbol
  • PTD012
  • PTOD012
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.19   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.19   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
CCT6A
Tbio
Novelty:  0.02368046
p_int:  0.7710588
p_ni:  0.2289412
Score:  0.564
Data Source:  BioPlex,STRINGDB
CCT3
Tbio
Novelty:  0.01642521
p_int:  0.754042127
p_ni:  0.245957873
Score:  0.392
Data Source:  BioPlex,STRINGDB
SERPINB5
Tbio
Novelty:  0.00192585
Score:  0.873
Data Source:  STRINGDB
AKR1C2
Tchem
Family:  Enzyme
Novelty:  0.00134228
Score:  0.871
Data Source:  STRINGDB
GNPDA2
Tbio
Family:  Enzyme
Novelty:  0.02712908
Score:  0.866
Data Source:  STRINGDB
PGM2
Tbio
Family:  Enzyme
Novelty:  0.00922421
Score:  0.823
Data Source:  STRINGDB
SERPINB3
Tbio
Novelty:  0.00325244
Score:  0.809
Data Source:  STRINGDB
ANXA7
Tbio
Novelty:  0.00365221
Score:  0.789
Data Source:  STRINGDB
TAF1B
Tbio
Family:  Enzyme
Novelty:  0.10174314
Score:  0.691
Data Source:  STRINGDB
DCXR
Tbio
Family:  Enzyme
Novelty:  0.00967328
Score:  0.679
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
1
1
2
78.9
educational attainment
1
1
1
20.5
smoking status measurement
1
1
1
18
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
2
78.9
educational attainment
1
20.5
smoking status measurement
1
18
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 11 C11orf54 homolog
VGNC:3181
451485
Macaque
chromosome 14 open reading frame, human C11orf54
696483
Mouse
MGI:1918234
70984
Rat
RGD:1309534
363016
Dog
chromosome 21 C11orf54 homolog
VGNC:52065
607137
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 11 C11orf54 homolog
Macaque
chromosome 14 open reading frame, human C11orf54
Mouse
Rat
Dog
chromosome 21 C11orf54 homolog
Publication Statistics
PubMed Score 2.19
PubMed score by year
PubTator Score 1.10
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title