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Tdark
C11orf24
Uncharacterized protein C11orf24

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304271
  • ENSP00000307264
  • ENSG00000171067

Symbol
  • DM4E3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.02   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.02   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
VAT1L
Tdark
Family:  Enzyme
Novelty:  0.45114244
p_int:  0.99997819
p_ni:  0.00002181
Score:  0.379
Data Source:  BioPlex,STRINGDB
RNF166
Tdark
Novelty:  0.71460884
p_int:  0.996099751
p_ni:  0.003887037
p_wrong:  0.000013212
Score:  0.189
Data Source:  BioPlex,STRINGDB
NME2P1
Tdark
Family:  Kinase
p_int:  0.950247546
p_ni:  0.04975245
p_wrong:  4e-9
Data Source:  BioPlex
VWA1
Tbio
Novelty:  0.00212445
p_int:  0.913490957
p_ni:  0.004062777
p_wrong:  0.082446266
Score:  0.214
Data Source:  BioPlex,STRINGDB
CCDC115
Tbio
Novelty:  0.23966137
Score:  0.652
Data Source:  STRINGDB
CREBL2
Tbio
Family:  TF
Novelty:  0.19415056
Score:  0.534
Data Source:  STRINGDB
ZNF616
Tdark
Family:  TF
Novelty:  3.98295142
Score:  0.528
Data Source:  STRINGDB
TMEM109
Tbio
Novelty:  0.2414463
Score:  0.52
Data Source:  STRINGDB
CDC14B
Tbio
Family:  Enzyme
Novelty:  0.12492348
Score:  0.484
Data Source:  STRINGDB
MED8
Tbio
Family:  Enzyme
Novelty:  0.06648307
Score:  0.463
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
3
6
96.9
bone density
2
1
2
93.1
1
1
0
1.1
90
testosterone measurement
4
2
3
6.9
87.7
1
1
0
1.2
50.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
6
96.9
bone density
2
93.1
0
1.1
90
testosterone measurement
3
6.9
87.7
0
1.2
50.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 11 C11orf24 homolog
VGNC:3175
451379
Macaque
chromosome 14 open reading frame, human C11orf24
721633
Mouse
MGI:1919306
72056
Rat
RGD:1311946
309145
Dog
chromosome 18 C11orf24 homolog
VGNC:51844
100682859
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 11 C11orf24 homolog
Macaque
chromosome 14 open reading frame, human C11orf24
Mouse
Rat
Dog
chromosome 18 C11orf24 homolog
Publication Statistics
PubMed Score 1.02
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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PMID
Year
Title