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Tdark
C10orf88
Uncharacterized protein C10orf88

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000481909
  • ENSP00000419126
  • ENSG00000119965
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.67   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.67   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
DOCK11
Tdark
Novelty:  0.0295159
p_int:  0.999999924
p_ni:  6.5e-8
p_wrong:  1.1e-8
Data Source:  BioPlex
DOCK9
Tbio
Novelty:  0.07297324
p_int:  0.999999916
p_ni:  8.4e-8
Score:  0.199
Data Source:  BioPlex,STRINGDB
NEDD1
Tbio
Novelty:  0.03077131
p_int:  0.999998308
p_ni:  0.000001692
p_wrong:  1e-9
Data Source:  BioPlex
CCDC91
Tbio
Novelty:  0.11171935
p_int:  0.991722688
p_ni:  0.00827731
p_wrong:  2e-9
Score:  0.217
Data Source:  BioPlex,STRINGDB
GDI2
Tbio
Novelty:  0.02861013
p_int:  0.980189479
p_ni:  0.019810521
Data Source:  BioPlex
NCKAP1
Tbio
Novelty:  0.03486454
p_int:  0.979203769
p_ni:  0.020796231
Data Source:  BioPlex
TINF2
Tbio
Novelty:  0.0064505
p_int:  0.974776597
p_ni:  0.025223402
p_wrong:  2e-9
Score:  0.165
Data Source:  BioPlex,STRINGDB
MAP2K5
Tchem
Family:  Kinase
Novelty:  0.00587774
p_int:  0.970569854
p_ni:  0.029430146
Data Source:  BioPlex
LILRB4
Tbio
Novelty:  0.01443658
p_int:  0.970569854
p_ni:  0.029430146
Data Source:  BioPlex
GIGYF2
Tchem
Novelty:  0.02395014
p_int:  0.969155191
p_ni:  0.030844807
p_wrong:  1e-9
Score:  0.795
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
4
96.5
low density lipoprotein cholesterol measurement
7
5
7
94.7
apolipoprotein B measurement
1
1
1
56.8
mean reticulocyte volume
1
1
1
56
reticulocyte measurement
1
1
1
48.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
96.5
low density lipoprotein cholesterol measurement
7
94.7
apolipoprotein B measurement
1
56.8
mean reticulocyte volume
1
56
reticulocyte measurement
1
48.5
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 10 C10orf88 homolog
VGNC:12277
743210
Macaque
chromosome 9 open reading frame, human C10orf88
707385
Mouse
MGI:1915527
68277
Rat
RGD:1305014
309029
Dog
chromosome 28 open reading frame, human C10orf88
611203
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 10 C10orf88 homolog
Macaque
chromosome 9 open reading frame, human C10orf88
Mouse
Rat
Dog
chromosome 28 open reading frame, human C10orf88
Publication Statistics
PubMed Score 1.67
PubMed score by year
PubTator Score 1.45
PubTator score by year
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Related Publications
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PMID
Year
Title