Tbio BUD13 BUD13 homolog

Protein Summary

Uniprot Accession IDs

• Q9BRD0
• A8K0S0
• Q96LS7

Gene Name

• BUD13

Ensembl ID

• ENST00000260210
• ENSP00000260210
• ENSG00000137656
• ENST00000375445
• ENSP00000364594

Symbol

• Cwc26
• fSAP71

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.87
ligand (protein) perturbation	0.83
virus perturbation	0.79
kinase perturbation	0.76
transcription factor binding site profile	0.75

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.04   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 83   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.04   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Protein Sequence and Structure

Residue Counts

Protein Sequence

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Expression Data (0 Tissues)

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No expression data found

Related Tools

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

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GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

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GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

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ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

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Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (146)

Explore Interacting Targets

1 – 10 of 146

• See Interactions on String-DB

RBMX2

Tbio

Novelty:  0.08867468

p_int:  0.999998637

p_ni:  0.000001363

Score:  0.998

Data Source:  BioPlex,STRINGDB

GPKOW

Tbio

Novelty:  0.14830491

p_int:  0.999919038

p_ni:  0.000079844

p_wrong:  0.000001118

Score:  0.693

Data Source:  BioPlex,STRINGDB

RPL14

Tbio

Novelty:  0.01600377

p_int:  0.998487543

p_ni:  0.001512457

Score:  0.555

Data Source:  BioPlex,STRINGDB

HIST1H1T

Tdark

Novelty:  0.01039464

p_int:  0.994415752

p_ni:  0.005584247

p_wrong:  1e-9

Data Source:  BioPlex

ZNF2

Tbio

Family:  TF

Novelty:  0.01062543

p_int:  0.989197465

p_ni:  0.010802522

p_wrong:  1.3e-8

Data Source:  BioPlex

WDR46

Tbio

Novelty:  0.19307408

p_int:  0.976086268

p_ni:  0.02391373

p_wrong:  2e-9

Data Source:  BioPlex

RPL37A

Tbio

Novelty:  0.03475061

p_int:  0.966156034

p_ni:  0.033843965

p_wrong:  1e-9

Score:  0.185

Data Source:  BioPlex,STRINGDB

NOL12

Tbio

Novelty:  0.15925205

p_int:  0.960886563

p_ni:  0.039113436

Score:  0.536

Data Source:  BioPlex,STRINGDB

ZNF512

Tbio

Family:  TF

Novelty:  0.08783629

p_int:  0.957845475

p_ni:  0.042154515

p_wrong:  1e-8

Score:  0.63

Data Source:  BioPlex,STRINGDB

RBM4

Tbio

Novelty:  0.02034191

p_int:  0.95397074

p_ni:  0.046029236

p_wrong:  2.5e-8

Data Source:  BioPlex

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (5)

Functions (1)

Components (3)

Processes (1)

Find Similar Targets

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GO Term	Evidence	Assigned by
RNA binding	Inferred from High Throughput Direct Assay (HDA)	UniProtKB

Disease Associations ()

No disease associations found

GWAS Traits (121)

• Explore on Target Illumination GWAS Analytics (TIGA)

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5

1 – 5 of 121

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
triglyceride measurement	EFO_0004530	55	67	172	12.3	100
high density lipoprotein cholesterol measurement	EFO_0004612	32	38	90	1.8	99.9
low density lipoprotein cholesterol measurement	EFO_0004611	15	13	20		99.8
apolipoprotein A 1 measurement	EFO_0004614	2	11	12		99.8
total cholesterol measurement	EFO_0004574	14	23	38	3.5	99.6

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 5 of 121

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
triglyceride measurement	EFO_0004530	172	12.3	100
high density lipoprotein cholesterol measurement	EFO_0004612	90	1.8	99.9
low density lipoprotein cholesterol measurement	EFO_0004611	20		99.8
apolipoprotein A 1 measurement	EFO_0004614	12		99.8
total cholesterol measurement	EFO_0004574	38	3.5	99.6

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Find similar targets by:

UniProt Keyword Find Similar Targets

No Header	No Header
3D-structure
Alternative splicing
Coiled coil
Complete proteome
Isopeptide bond
Phosphoprotein
Polymorphism
Reference proteome
Ubl conjugation

GWAS Trait Find Similar Targets

No Header	No Header
Abdominal Aortic Aneurysm
adiponectin measurement
Agents acting on the renin-angiotensin system use measurement
alkaline phosphatase measurement
amino acid measurement
antioxidant measurement
Antithrombotic agent use measurement
apolipoprotein A 1 measurement
apolipoprotein A-IV measurement
apolipoprotein B measurement

IDG Resources

No IDG generated resources found

Orthologs (14)

1 – 5 of 14

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	BUD13 homolog	VGNC:3197	451562
Mouse	BUD13 homolog	MGI:2443443	215051
Rat	BUD13 homolog	RGD:1308076	300687
Dog	BUD13 homolog	VGNC:38568	479429
Horse	BUD13 homolog	VGNC:15927	100062438

Species	Name	OMA	EggNOG	Inparanoid
Chimp	BUD13 homolog
Mouse	BUD13 homolog
Rat	BUD13 homolog
Dog	BUD13 homolog
Horse	BUD13 homolog

Publication Statistics

PubMed Score 21.04

PubMed score by year

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PubTator Score 8.83

PubTator score by year

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Related Publications

Text Mined References (37)

GeneRif Annotations (10)

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10

0 of 0

PMID	Year	Title