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Tdark
BTNL3
Butyrophilin-like protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000342868
  • ENSP00000341787
  • ENSG00000168903

Symbol
  • BTNLR
  • COLF4100
  • BTNLR
  • BTN9.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
cell line
0.51
microRNA
0.49
disease perturbation
0.43
cell type or tissue
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.25   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 143   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.25   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 143   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
SLC25A51
Tbio
Family:  Transporter
Novelty:  0.21568087
p_int:  0.99981364
p_ni:  0.000186347
p_wrong:  1.3e-8
Score:  0.188
Data Source:  BioPlex,STRINGDB
ITGA5
Tbio
Novelty:  0.00285802
p_int:  0.999652221
p_ni:  0.000347021
p_wrong:  7.58e-7
Score:  0.19
Data Source:  BioPlex,STRINGDB
ABCA2
Tbio
Family:  Transporter
Novelty:  0.02208136
p_int:  0.999412348
p_ni:  0.000585263
p_wrong:  0.000002389
Data Source:  BioPlex
CYP20A1
Tbio
Novelty:  0.11080329
p_int:  0.997402112
p_ni:  0.00253986
p_wrong:  0.000058029
Score:  0.309
Data Source:  BioPlex,STRINGDB
CGRRF1
Tdark
Novelty:  0.49690187
p_int:  0.996260587
p_ni:  0.003641378
p_wrong:  0.000098034
Data Source:  BioPlex
FAM171A2
Tdark
Novelty:  1.18763693
p_int:  0.99145172
p_ni:  0.00854825
p_wrong:  3.1e-8
Score:  0.169
Data Source:  BioPlex,STRINGDB
ITGA6
Tbio
Novelty:  0.00217985
p_int:  0.986717341
p_ni:  0.013282659
Data Source:  BioPlex
SEMA6A
Tbio
Novelty:  0.00624456
p_int:  0.984879865
p_ni:  0.015110923
p_wrong:  0.000009211
Data Source:  BioPlex
PDZD8
Tbio
Novelty:  0.09015543
p_int:  0.982851855
p_ni:  0.017148145
Data Source:  BioPlex
DAG1
Tbio
Family:  Enzyme
Novelty:  0.00149278
p_int:  0.978726524
p_ni:  0.021241189
p_wrong:  0.000032287
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein A 1 measurement
1
1
1
62.1
high density lipoprotein cholesterol measurement
1
1
1
55.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein A 1 measurement
1
62.1
high density lipoprotein cholesterol measurement
1
55.2
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
butyrophilin like 3
VGNC:6384
741298
Macaque
butyrophilin like 3 [Source:HGNC Symbol;Acc:HGNC:1143]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
butyrophilin like 3
Macaque
butyrophilin like 3 [Source:HGNC Symbol;Acc:HGNC:1143]
Publication Statistics
PubMed Score 4.25
PubMed score by year
PubTator Score 1.40
PubTator score by year
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Related Publications
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PMID
Year
Title