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Tchem
BRPF3
Bromodomain and PHD finger-containing protein 3

Protein Summary
Description
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339717
  • ENSP00000345419
  • ENSG00000096070
  • ENST00000357641
  • ENSP00000350267
  • ENST00000534694
  • ENSP00000434501

Symbol
  • KIAA1286
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
transcription factor binding site profile
0.78
histone modification site profile
0.75
tissue sample
0.67
microRNA
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 11
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0