Tchem BRPF3 Bromodomain and PHD finger-containing protein 3

Protein Summary

Description

Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.

Uniprot Accession IDs

• Q9ULD4
• A6ND56
• A6NJE2
• B7ZLN5
• E7EX85
• Q17RB6
• Q5R3K8

Gene Name

• BRPF3

Ensembl ID

• ENST00000339717
• ENSP00000345419
• ENSG00000096070
• ENST00000357641
• ENSP00000350267
• ENST00000534694
• ENSP00000434501

Symbol

• KIAA1286

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.99
transcription factor binding site profile	0.78
histone modification site profile	0.75
tissue sample	0.67
microRNA	0.64

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / Bromodomain And Phd Finger-containing Protein 3

Protein / Nucleic Acid Binding / Bromodomain And Phd Finger-containing Protein 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.47   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 76   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.47   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 11

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0