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Tbio
BORCS7
BLOC-1-related complex subunit 7

Protein Summary
Description
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339834
  • ENSP00000342331
  • ENSG00000166275
  • ENST00000369883
  • ENSP00000358899

Symbol
  • C10orf32
  • C10orf32
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.62   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.62   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
BORCS5
Tdark
Novelty:  0.59333419
p_int:  0.999999973
p_ni:  2.6e-8
p_wrong:  1e-9
Score:  0.968
Data Source:  BioPlex,STRINGDB
KXD1
Tbio
Novelty:  0.32146379
p_int:  0.99999992
p_ni:  8e-8
Score:  0.965
Data Source:  BioPlex,STRINGDB
BLOC1S2
Tbio
Novelty:  0.02346362
p_int:  0.999999892
p_ni:  1.06e-7
p_wrong:  2e-9
Score:  0.951
Data Source:  BioPlex,STRINGDB
BORCS8
Tdark
Novelty:  1.62939642
p_int:  0.99999979
p_ni:  2.1e-7
Score:  0.968
Data Source:  BioPlex,STRINGDB
TEX35
Tbio
Novelty:  0.5605055
p_int:  0.999999647
p_ni:  3.31e-7
p_wrong:  2.2e-8
Score:  0.202
Data Source:  BioPlex,STRINGDB
BLOC1S1
Tbio
Novelty:  0.02921036
p_int:  0.999999565
p_ni:  4.35e-7
Score:  0.957
Data Source:  BioPlex,STRINGDB
IKBIP
Tbio
Family:  Enzyme
Novelty:  0.18707639
p_int:  0.999997002
p_ni:  0.000002971
p_wrong:  2.8e-8
Data Source:  BioPlex
SNAPIN
Tbio
Novelty:  0.02019383
p_int:  0.999995481
p_ni:  0.000004518
Score:  0.956
Data Source:  BioPlex,STRINGDB
BORCS6
Tdark
Novelty:  0.83789033
p_int:  0.999989849
p_ni:  1.2e-8
p_wrong:  0.00001014
Score:  0.966
Data Source:  BioPlex,STRINGDB
PRUNE1
Tchem
Novelty:  0.02136836
p_int:  0.999984889
p_ni:  0.000015111
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (64)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
8
6
4
1.1
97.9
schizophrenia
12
8
3
1.1
97.5
3
3
2
1.1
96.2
testosterone measurement
8
4
7
8.9
94.3
body mass index
6
4
7
92.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
1.1
97.9
schizophrenia
3
1.1
97.5
2
1.1
96.2
testosterone measurement
7
8.9
94.3
body mass index
7
92.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 7.62
PubMed score by year
PubTator Score 2.15
PubTator score by year
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Related Publications
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PMID
Year
Title