BORA
Protein aurora borealis
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.89 | ||
virus perturbation | 0.88 | ||
trait | 0.75 | ||
kinase | 0.68 | ||
tissue | 0.59 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | G2/M Transition | ||||
Reactome | Mitotic G2-G2/M phases | ||||
Reactome | Regulation of PLK1 Activity at G2/M Transition | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
G2/M Transition | ||||
Mitotic G2-G2/M phases | ||||
Regulation of PLK1 Activity at G2/M Transition | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean reticulocyte volume | 1 | 1 | 1 | 71.2 | |||||
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 32.9 | |||||
testosterone measurement | 1 | 1 | 1 | 6.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean reticulocyte volume | 1 | 71.2 | |||||
mean corpuscular hemoglobin concentration | 1 | 32.9 | |||||
testosterone measurement | 1 | 6.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | bora, aurora kinase A activator | VGNC:9842 | 467283 | |||||
Macaque | bora, aurora kinase A activator | 693798 | ||||||
Mouse | MGI:1924994 | 77744 | ||||||
Rat | RGD:1309522 | 306102 | ||||||
Dog | bora, aurora kinase A activator | VGNC:38499 | 476944 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | bora, aurora kinase A activator | |||||
Macaque | bora, aurora kinase A activator | |||||
Mouse | ||||||
Rat | ||||||
Dog | bora, aurora kinase A activator | |||||
PMID | Year | Title |
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