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Tbio
BNC2
Zinc finger protein basonuclin-2

Protein Summary
Description
Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes. This gene encodes a conserved zinc finger protein. The encoded protein functions in skin color saturation. Mutations in this gene are associated with facial pigmented spots. This gene is also associated with susceptibility to adolescent idiopathic scoliosis. [provided by RefSeq, Jul 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380672
  • ENSP00000370047
  • ENSG00000173068
  • ENST00000484726
  • ENSP00000431516

Symbol
  • BSN2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
transcription factor perturbation
0.74
PubMedID
0.71
disease
0.65
histone modification site profile
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 76.96   (req: < 5)
Gene RIFs: 23   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 76.96   (req: >= 5)
Gene RIFs: 23   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0