Tchem BIRC8 Baculoviral IAP repeat-containing protein 8

Protein Summary

Description

Protects against apoptosis mediated by BAX.

Uniprot Accession IDs

• Q96P09
• Q6IPY1
• Q96RW5

Gene Name

• BIRC8

Ensembl ID

• ENST00000426466
• ENSP00000412957
• ENSG00000163098

Symbol

• ILP2
• ILP2
• ILP-2
• hILP2
• RNF136

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.84
biological process	0.75
cell line	0.41
cell type or tissue	0.41
tissue sample	0.4

Protein Classes

PANTHER Classes

Protein / Enzyme Modulator / Protease Inhibitor / Baculoviral Iap Repeat-containing Protein 8

DTO Classes

Protein / Enzyme Modulator / Protease Inhibitor / Baculoviral Iap Repeat-containing Protein 8

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.5   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 183   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.5   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 183   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 6

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0