BHMT2
S-methylmethionine--homocysteine S-methyltransferase BHMT2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.58 | ||
PubMedID | 0.58 | ||
cell type or tissue | 0.57 | ||
molecular function | 0.56 | ||
microRNA | 0.54 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Sulfur amino acid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
Sulfur amino acid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
selenium measurement | 1 | 3 | 3 | 83.1 | |||||
serum selenium measurement | 1 | 1 | 1 | 78.5 | |||||
2 | 2 | 1 | 1.1 | 76.2 | |||||
blood metabolite measurement | 1 | 1 | 1 | 71.9 | |||||
plasma betaine measurement | 1 | 1 | 1 | 56.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
selenium measurement | 3 | 83.1 | |||||
serum selenium measurement | 1 | 78.5 | |||||
1 | 1.1 | 76.2 | |||||
blood metabolite measurement | 1 | 71.9 | |||||
plasma betaine measurement | 1 | 56.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | betaine--homocysteine S-methyltransferase 2 | VGNC:6382 | 471829 | |||||
Macaque | betaine--homocysteine S-methyltransferase 2 | 714308 | ||||||
Mouse | MGI:1891379 | 64918 | ||||||
Rat | RGD:1359418 | 365972 | ||||||
Dog | betaine--homocysteine S-methyltransferase 2 | VGNC:38448 | 488934 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | betaine--homocysteine S-methyltransferase 2 | |||||
Macaque | betaine--homocysteine S-methyltransferase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | betaine--homocysteine S-methyltransferase 2 | |||||
PMID | Year | Title |
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