Protein Summary
Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity). This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- ENST00000222547
- ENSP00000222547
- ENSG00000105829
- ENST00000433727
- ENSP00000391228
- HBET1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.83 | ||
interacting protein | 0.82 | ||
histone modification site profile | 0.8 | ||
transcription factor binding site profile | 0.78 | ||
cellular component | 0.75 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 51.74 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 34 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 51.74 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 34 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (200)
SEC22B
Novelty: 0.03035448
p_int: 0.999922949
p_ni: 0.000076954
p_wrong: 9.7e-8
Score: 0.995
Data Source: BioPlex,Reactome,STRINGDB
STX18
Novelty: 0.0259034
p_int: 0.999874073
p_ni: 0.000125869
p_wrong: 5.8e-8
Score: 0.926
Data Source: BioPlex,STRINGDB
TRDN
Novelty: 0.00501554
p_int: 0.9649414
p_ni: 0.034634219
p_wrong: 0.000424381
Data Source: BioPlex
IL20RA
Novelty: 0.02416816
p_int: 0.963180199
p_ni: 0.036324633
p_wrong: 0.000495168
Data Source: BioPlex
IFT20
Novelty: 0.03005088
p_int: 0.929150652
p_ni: 0.05874046
p_wrong: 0.012108889
Data Source: BioPlex
CHRNB1
Family: IC
Novelty: 0.04777051
p_int: 0.927043188
p_ni: 0.058027908
p_wrong: 0.014928903
Data Source: BioPlex
HAUS1
Novelty: 0.11356375
p_int: 0.884023399
p_ni: 0.11541869
p_wrong: 0.000557911
Score: 0.173
Data Source: BioPlex,STRINGDB
MANSC1
Novelty: 0.91681036
p_int: 0.865997253
p_ni: 0.001801338
p_wrong: 0.132201409
Data Source: BioPlex
COX4I1
Family: Enzyme
Novelty: 0.00208873
p_int: 0.864841576
p_ni: 0.008981119
p_wrong: 0.126177305
Data Source: BioPlex
ADGRE5
Family: GPCR
Novelty: 0.01137558
p_int: 0.85609226
p_ni: 0.002282381
p_wrong: 0.141625359
Data Source: BioPlex
Nearest Tclin Targets
Pathways (10)
Reactome (9)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Asparagine N-linked glycosylation | ||||
Reactome | COPI-mediated anterograde transport | ||||
Reactome | COPII-mediated vesicle transport | ||||
Reactome | ER to Golgi Anterograde Transport | ||||
Reactome | Membrane Trafficking | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Asparagine N-linked glycosylation | ||||
COPI-mediated anterograde transport | ||||
COPII-mediated vesicle transport | ||||
ER to Golgi Anterograde Transport | ||||
Membrane Trafficking | ||||
Viral Interactions (0)
Gene Ontology Terms (9)
Components (6)
Processes (3)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (3)
Items per page:
1 – 3 of 3
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heart rate variability measurement | 3 | 2 | 6 | 75.9 | |||||
heart rate response to recovery post exercise | 5 | 2 | 5 | 57.6 | |||||
heart rate | 1 | 1 | 1 | 12.7 | |||||
Items per page:
1 – 3 of 3
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heart rate variability measurement | 6 | 75.9 | |||||
heart rate response to recovery post exercise | 5 | 57.6 | |||||
heart rate | 1 | 12.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | Bet1 golgi vesicular membrane trafficking protein | 700492 | ||||||
Mouse | MGI:1343104 | 12068 | ||||||
Rat | RGD:2203 | 29631 | ||||||
Cow | Bet1 golgi vesicular membrane trafficking protein | VGNC:26475 | 616526 | |||||
Opossum | Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | Bet1 golgi vesicular membrane trafficking protein | |||||
Mouse | ||||||
Rat | ||||||
Cow | Bet1 golgi vesicular membrane trafficking protein | |||||
Opossum | Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562] | |||||
Publication Statistics
PubMed Score 51.74
PubMed score by year
PubTator Score 126.97
PubTator score by year
Related Publications
Text Mined References (19)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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