Tbio BEGAIN Brain-enriched guanylate kinase-associated protein

Protein Summary

Description

May sustain the structure of the postsynaptic density (PSD).

Uniprot Accession IDs

• Q9BUH8
• Q9NPU3
• Q9P282

Gene Name

• BEGAIN

Ensembl ID

• ENST00000355173
• ENSP00000347301
• ENSG00000183092
• ENST00000443071
• ENSP00000411124

Symbol

• KIAA1446

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
ligand (protein) perturbation	0.83
cell type or tissue	0.64
tissue sample	0.54
cellular component	0.52
cell line	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.87   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 113   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.87   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0