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Tdark
BCLAF3
BCLAF1 and THRAP3 family member 3

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.65   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 32   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.65   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
ERH
Tbio
Novelty:  0.00711649
p_int:  0.999964462
p_ni:  1.9e-8
p_wrong:  0.00003552
Data Source:  BioPlex
EFHC2
Tbio
Novelty:  0.08795794
Score:  0.727
Data Source:  STRINGDB
MAP7D2
Tdark
Novelty:  0.70744439
Score:  0.679
Data Source:  STRINGDB
CA5B
Tclin
Family:  Enzyme
Novelty:  0.01741841
Score:  0.66
Data Source:  STRINGDB
EIF1AX
Tbio
Novelty:  0.01945373
Score:  0.604
Data Source:  STRINGDB
RPS6KA6
Tchem
Family:  Kinase
Novelty:  0.03326451
Score:  0.563
Data Source:  STRINGDB
DMD
Tclin
Novelty:  0.00025661
Score:  0.561
Data Source:  STRINGDB
CFAP47
Tdark
Novelty:  0.59170159
Score:  0.559
Data Source:  STRINGDB
ASB11
Tdark
Novelty:  0.84862254
Score:  0.559
Data Source:  STRINGDB
CASK
Tchem
Family:  Kinase
Novelty:  0.00856437
Score:  0.556
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
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10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
1
1
1
39.6
platelet count
1
1
1
36.9
hematocrit
1
1
1
35
mean platelet volume
1
1
1
9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
1
39.6
platelet count
1
36.9
hematocrit
1
35
mean platelet volume
1
9
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
BCLAF1 and THRAP3 family member 3
VGNC:2723
739784
Macaque
BCLAF1 and THRAP3 family member 3
696449
Mouse
MGI:2685992
382252
Rat
RGD:1562161
501559
Dog
BCLAF1 and THRAP3 family member 3
VGNC:38416
611699
Species
Name
OMA
EggNOG
Inparanoid
Chimp
BCLAF1 and THRAP3 family member 3
Macaque
BCLAF1 and THRAP3 family member 3
Mouse
Rat
Dog
BCLAF1 and THRAP3 family member 3
Publication Statistics
PubMed Score 0.65
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title