BCL2L14
Apoptosis facilitator Bcl-2-like protein 14
Protein Summary
Plays a role in apoptosis. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]
- ENST00000266434
- ENSP00000266434
- ENSG00000121380
- ENST00000298566
- ENSP00000298566
- ENST00000308721
- ENSP00000309132
- ENST00000396367
- ENSP00000379653
- ENST00000589718
- ENSP00000467086
- ENST00000627413
- ENSP00000486050
- ENSG00000281449
- ENST00000628315
- ENSP00000485980
- ENST00000628783
- ENSP00000487330
- ENST00000631251
- ENSP00000486560
- ENST00000631317
- ENSP00000486796
- BCLG
- BCLG
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 1 | ||
tissue sample | 0.81 | ||
PubMedID | 0.65 | ||
cell type or tissue | 0.57 | ||
gene perturbation | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 27.45 (req: < 5)
Gene RIFs: 17 (req: <= 3)
Antibodies: 249 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 27.45 (req: >= 5)
Gene RIFs: 17 (req: > 3)
Antibodies: 249 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0